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TLR

Chemical Structure Cat. No. Product Name CAS No.
Gardiquimod TFA Chemical Structure
 BCP30186 Gardiquimod TFA 1159840-61-5
Gardiquimod trifluoroacetate is a specific TLR7 agonist which can also inhibit HIV-1 reverse transcriptase.
Gardiquimod Chemical Structure
 BCP30187 Gardiquimod 1020412-43-4
Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier.
CU-T12-9 Chemical Structure
 BCP16577 CU-T12-9 1821387-73-8
CU-T12-9 is a potent TLR1/2 agonist (EC50 = 52.9 nM).
MD2-IN-1 Chemical Structure
 BCP29883 MD2-IN-1 111797-22-9
MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189  μM for the recombinant human MD2 (rhMD2).
Isatoribine Chemical Structure
 BCP07972 Isatoribine 122970-40-5
Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection.
Isatoribine hydrate Chemical Structure
 BCP29841 Isatoribine hydrate 198832-38-1
Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection.
E6446 HCl Chemical Structure
 BCP29147 E6446 HCl 1345675-25-3
E6446 is a synthetic antagonist of nucleic acid-sensing TLRs.
E6446 Chemical Structure
 BCP29146 E6446 1219925-73-1
E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling.
Golotimod Chemical Structure
 BCP24651 Golotimod 229305-39-9
Golotimod is a novel synthetic dipeptide that acts broadly on the Toll-like receptor pathway. It has been shown to stimulate T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 and INF-g production.
Resatorvid Chemical Structure
 BCP22627 Resatorvid 243984-11-4
Resatorvid is a potent TLR4 signaling inhibitor, selectively inhibits the TLR4-mediated production of cytokines and NO.
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