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TLR

Chemical Structure Cat. No. Product Name CAS No.
MD2-IN-1 Chemical Structure
 BCP29883 MD2-IN-1 111797-22-9
MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189  μM for the recombinant human MD2 (rhMD2).
Isatoribine Chemical Structure
 BCP07972 Isatoribine 122970-40-5
Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection.
Isatoribine hydrate Chemical Structure
 BCP29841 Isatoribine hydrate 198832-38-1
Isatoribine, an agonist of TLR7, reduces plasma virus concentration in chronic hepatitis C infection.
E6446 HCl Chemical Structure
 BCP29147 E6446 HCl 1345675-25-3
E6446 is a synthetic antagonist of nucleic acid-sensing TLRs.
E6446 Chemical Structure
 BCP29146 E6446 1219925-73-1
E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling.
Golotimod Chemical Structure
 BCP24651 Golotimod 229305-39-9
Golotimod is a novel synthetic dipeptide that acts broadly on the Toll-like receptor pathway. It has been shown to stimulate T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 and INF-g production.
Resatorvid Chemical Structure
 BCP22627 Resatorvid 243984-11-4
Resatorvid is a potent TLR4 signaling inhibitor, selectively inhibits the TLR4-mediated production of cytokines and NO.
CU-CPT17e Chemical Structure
 BCP29395 CU-CPT17e 2109805-75-4
CU-CPT17e is a multi-Toll-like receptors (TLRs) agonist that activates TLR3, TLR8, and TLR9.
Paquinimod Chemical Structure
 BCP29381 Paquinimod 248282-01-1
Paquinimod is a S100A9 inhibitor, which prevents S100A9 binding to TLR-4.
Procyanidin B1 Chemical Structure
 BCP29179 Procyanidin B1 20315-25-7
Procyanidin B1 , inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with IC50 of 29μM and 15μM, respectively.
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