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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
Donafenib Chemical Structure
BCP34023 Donafenib 1130115-44-4
Donafenib is an oral multikinase inhibitor that targets Raf kinase and receptor tyrosine kinases with potential anticancer acivity. Donafenib is under clinical trials in China in patients with advanced hepatocellular carcinoma (HCC).
BMS-1001 Chemical Structure
BCP33668 BMS-1001 2113650-03-4
BMS-1001 is a potent PD-1/PD-L1 interaction inhibitor.
BMS1001 hydrochloride Chemical Structure
BCP33667 BMS1001 hydrochloride 2113650-04-5
BMS-1001 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor.
Corilagin Chemical Structure
BCP25487 Corilagin 23094-69-1
Corilagin, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. It is an inhibitor of TNF-α.
BTZO-1 Chemical Structure
BCP33285 BTZO-1 99420-15-2
BTZO-1 is an activator of the glutathione S-transferase Ya subunit (GST Ya) gene ARE by interacting with MIF.
BDA-366 Chemical Structure
BCP25061 BDA-366 1821496-27-8
BDA-366 is a Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy.
PTC596 Chemical Structure
BCP33231 PTC596 1610964-64-1
PTC596 is a novel BMI-1 inhibitor, downregulating MCL-1 and inducing p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells.
MBM-55 Chemical Structure
BCP32925 MBM-55 2083622-09-5
MBM-55 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM.
Bz-423 Chemical Structure
BCP25995 Bz-423 216691-95-1
Bz-423 is an F1F0-ATPase modulator. It acts by selectively killing autoimmune lymphocytes.
Necrostatin 2 racemate Chemical Structure
BCP26072 Necrostatin 2 racemate 852391-15-2
Necrostatin 2 racemate (Nec-1S), the Nec-1 stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect.
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