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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
Pifithrin-β hydrobromide Chemical Structure
BCP17578 Pifithrin-β hydrobromide 511296-88-1
Pifithrin-β is a potent p53 inhibitor with an IC50 of 23 μM.
10074-G5 Chemical Structure
BCP09223 10074-G5 413611-93-5
10074-G5 is an inhibitor of c-Myc-Max dimerization with an IC50 of 146 μM.
CP 31398 Chemical Structure
BCP14611 CP 31398 259199-65-0
CP 31398 dihydrochloride is a potent activator of p53 with maximum tolerated dose of 400 ppm.
AX-024 Chemical Structure
BCP30051 AX-024 1370544-73-2
AX-024 is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
AX-024 hydrochloride Chemical Structure
BCP30050 AX-024 hydrochloride 1704801-24-0
AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
Tpl2 Kinase Inhibitor Chemical Structure
BCP16321 Tpl2 Kinase Inhibitor 871307-18-5
Tpl2 Kinase Inhibitor is a potent, selective, reversible and ATP-competitive inhibitor of Tpl2 kinase with IC50 of 50 nM.
Erastin Chemical Structure
BCP27907 Erastin 571203-78-6
Erastin is a ferroptosis activator.
RSL3 Chemical Structure
BCP18763 RSL3 1219810-16-8
RSL3 is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.
FIN-56 Chemical Structure
BCP29145 FIN-56 1083162-61-1
FIN-56 is a specific inducer of ferroptosis.
Liproxstatin-1 Chemical Structure
BCP15985 Liproxstatin-1 950455-15-9
Liproxstatin-1 is a potent ferroptosis inhibitor in cells, in Gpx4(-/-) mice, and in a pre-clinical model of ischaemia/reperfusion-induced hepatic damage.
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