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COX

Chemical Structure Cat. No. Product Name CAS No.
Flunoxaprofen Chemical Structure
BCP30327 Flunoxaprofen 66934-18-7
Flunoxaprofen is a chiral nonsteroidal anti-inflammatory drug (NSAID) that is closely related to naproxen. Flunoxaprofen has been shown to significantly improve the symptoms of osteoarthritis and rheumatoid arthritis.
Amtolmetin guacil Chemical Structure
BCP28767 Amtolmetin guacil 87344-06-7
Amtolmetin guacil is a N-acyl-amino acid.
Dipyrone sodium hydrate Chemical Structure
BCP11981 Dipyrone sodium hydrate 5907-38-0
Dipyrone sodium hydrate is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).
Diclofenac Chemical Structure
BCP09087 Diclofenac 15307-86-5
Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively.
Mavacoxib Chemical Structure
BCP15454 Mavacoxib 170569-88-7
Mavacoxib is a veterinary drug used to treat pain and inflammation in dogs with degenerative joint disease. It acts as a COX-2 inhibitor.
Aspirin DL-lysine Chemical Structure
BCP12010 Aspirin DL-lysine 62952-06-1
Aspirin DL-lysine is a non-steroidal anti-inflammatory drug (NSAIDs) that may inhibit cancer growth. Aspirin DL-lysine is a water soluble, injectable aspirin derivative. It is an analgesic; antipyretic; anti-inflammatory.
Antrafenine Chemical Structure
BCP09255 Antrafenine 55300-29-3
Antrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen. Antrafenine is believed to be associated with the inhibition of cyclooxygenase activity. Two unique cyclooxygenases have been described in mammals. The constitutive cyclooxygenase, COX-1, synthesizes prostaglandins necessary for normal gastrointestinal and renal function. The inducible cyclooxygenase, COX-2, generates prostaglandins involved in inflammation. Inhibition of COX-1 is thought to be associated with gastrointestinal and renal toxicity while inhibition of COX-2 provides anti-inflammatory activity.
Licofelone Chemical Structure
BCP06598 Licofelone 156897-06-2
Licofelone (ML3000) is a dual COX/LOX inhibitor and the first member of this new class of analgesic and anti-inflammatory drugs.
TFAP Chemical Structure
BCP30148 TFAP 1011244-68-0
TFAP is a selective cyclooxygenase-1 (COX-1) inhibitor, with an IC50 of 0.8 μM.
Ibuprofen lysine Chemical Structure
BCP27681 Ibuprofen lysine 57469-77-9
Ibuprofen Lysine is a non-steroidal anti-inflammatory drug.
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