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COX

Chemical Structure Cat. No. Product Name CAS No.
Parecoxib sodium Chemical Structure
BCP06888 Parecoxib sodium 198470-85-8
Parecoxib is a potent and selective COX-2 inhibitor.
Aminoprofen Chemical Structure
BCP35848 Aminoprofen 83394-44-9
Aminoprofen is an NSAID (non-steroidal anti-inflammatory drug) and non selective COX inhibitor.
Tiaprofenic acid Chemical Structure
BCP35787 Tiaprofenic acid 33005-95-7
Tiaprofenic acid is an orally active nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic potency. Tiaprofenic acid inhibits prostaglandin synthesis by suppressing cyclo-oxygenase (COX). Tiaprofenic acid can be used in the treatment of rheumatic diseases.
FR 122047 hydrochloride Chemical Structure
BCP35730 FR 122047 hydrochloride 130717-51-0
FR-122047 is a selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.028 and 65 μM for COX-1 and COX-2 respectively). Antiplatelet, analgesic and anti-inflammatory following oral administration in vivo.
Loxoprofen Chemical Structure
BCP10971 Loxoprofen 68767-14-6
Loxoprofen is a non-steroidal anti-inflammatory drug.
(S)-(+)-Ibuprofen Chemical Structure
BCP25225 (S)-(+)-Ibuprofen 51146-56-6
(S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects.
Rebamipide Chemical Structure
BCP12128 Rebamipide 111911-87-6
Rebamipide is an enhancer of mucosal defense, scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2.
Guaiacol Chemical Structure
BCP27082 Guaiacol 90-05-1
Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.
Naproxen sodium Chemical Structure
BCP23430 Naproxen sodium 26159-34-2
Naproxen sodium is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.
20(S)-Ginsenoside C-K Chemical Structure
BCP30926 20(S)-Ginsenoside C-K 39262-14-1
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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