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AKT

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AKT

Chemical Structure Cat. No. Product Name CAS No.
Ipatasertib dihydrochloride Chemical Structure
BCP23821 Ipatasertib dihydrochloride 1396257-94-5
Ipatasertib dihydrochloride is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
Recilisib Chemical Structure
BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
AT7867 dihydrochloride Chemical Structure
BCP30936 AT7867 dihydrochloride 1431697-86-7
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
LM22B-10 Chemical Structure
BCP30139 LM22B-10 342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
PIT 1 Chemical Structure
BCP27689 PIT 1 53501-41-0
PIT-1 is a selective nonphosphoinositide inhibitor that specifically disrupts PIP3/Akt PH domain binding with an IC50 value of 31 μM.
MK-2206 Chemical Structure
BCP20200 MK-2206 1032349-93-1
MK-2206 is a highly selective inhibitor of pan-Akt, namely, of all three Akt isoforms Akt1, Akt2, and Akt3.
Akt-I-2 HCl Chemical Structure
BCP18315 Akt-I-2 HCl 473382-50-2
Akt-I-1,2 is a selective Akt1 and Akt2 inhibitor.
BAY-1125976 Chemical Structure
BCP20659 BAY-1125976 1402608-02-9
BAY1125976 is a selective allosteric Akt1/2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively.
UCN-01 Chemical Structure
BCP14345 UCN-01 112953-11-4
UCN-01 (7-hydroxystaurosporine) acts as an inhibitor against many phosphokinases, such as the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases.
Uprosertib hydrochloride Chemical Structure
BCP28203 Uprosertib hydrochloride 1047635-80-2
Uprosertib hydrochloride is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.
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