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AKT

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AKT

Chemical Structure Cat. No. Product Name CAS No.
Recilisib sodium Chemical Structure
BCP35048 Recilisib sodium 922139-31-9
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
E-Guggulsterone Chemical Structure
BCP34834 E-Guggulsterone 39025-24-6
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii.
(Z)-Guggulsterone Chemical Structure
BCP07472 (Z)-Guggulsterone 39025-23-5
Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Miransertib HCl Chemical Structure
BCP25709 Miransertib HCl 1313883-00-9
Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively.
Ipatasertib dihydrochloride Chemical Structure
BCP23821 Ipatasertib dihydrochloride 1396257-94-5
Ipatasertib dihydrochloride is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA.
Recilisib Chemical Structure
BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
AT7867 dihydrochloride Chemical Structure
BCP30936 AT7867 dihydrochloride 1431697-86-7
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/Akt2/Akt3 and p70S6K/PKA with IC50s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.
LM22B-10 Chemical Structure
BCP30139 LM22B-10 342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
PIT 1 Chemical Structure
BCP27689 PIT 1 53501-41-0
PIT-1 is a selective nonphosphoinositide inhibitor that specifically disrupts PIP3/Akt PH domain binding with an IC50 value of 31 μM.
MK-2206 Chemical Structure
BCP20200 MK-2206 1032349-93-1
MK-2206 is a highly selective inhibitor of pan-Akt, namely, of all three Akt isoforms Akt1, Akt2, and Akt3.
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