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AKT

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AKT

Chemical Structure Cat. No. Product Name CAS No.
Akt-I-2 HCl Chemical Structure
BCP18315 Akt-I-2 HCl 473382-50-2
Akt-I-1,2 is a selective Akt1 and Akt2 inhibitor.
BAY-1125976 Chemical Structure
BCP20659 BAY-1125976 1402608-02-9
BAY1125976 is a selective allosteric Akt1/2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively.
UCN-01 Chemical Structure
BCP14345 UCN-01 112953-11-4
UCN-01 (7-hydroxystaurosporine) acts as an inhibitor against many phosphokinases, such as the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases.
Uprosertib hydrochloride Chemical Structure
BCP28203 Uprosertib hydrochloride 1047635-80-2
Uprosertib hydrochloride is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.
Uprosertib Chemical Structure
BCP28204 Uprosertib 1047634-65-0
Uprosertib is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.
M2698 Chemical Structure
BCP19488 M2698 1379545-95-5
M2698, also known as MSC-2363318A, is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier.
NSC177223 Chemical Structure
BCP24669 NSC177223 36707-00-3
NSC177233 is a potent Akt inhibitor, which induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
Oridonin Chemical Structure
BCP01044 Oridonin 28957-04-2
Oridonin, an entkaurane diterpenoid isolated from Rabdosia rubescens, is an important traditional Chinese herbal remedy.
GSK-2110183 Chemical Structure
BCP09279 GSK-2110183 1047630-52-3
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively.
Scutellarin Chemical Structure
BCP11536 Scutellarin 27740-01-8
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts.
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