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mTOR

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mTOR

Chemical Structure Cat. No. Product Name CAS No.
3BDO Chemical Structure
 BCP29764 3BDO 890405-51-3
3BDO is a new mTOR activator which can also inhibit autophagy.
GNE-490 Chemical Structure
 BCP21623 GNE-490 1033739-92-2
GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR.
GNE-317 Chemical Structure
 BCP23939 GNE-317 1394076-92-6
GNE-317 is a PI3K/mTOR inhibitor, is able to cross the blood-brain barrier (BBB).
PQR530 Chemical Structure
 BCP20879 PQR530 1927857-61-1
PQR-530 is a potent, oral and brain-penetrant dual pan-PI3K/mTORC1/2 inhibitor, exhibiting antitumor activity.
LY 303511 Chemical Structure
 BCP08239 LY 303511 154447-38-8
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K.
LY 303511 hydrochloride Chemical Structure
 BCP25465 LY 303511 hydrochloride LY303511HCl
LY 303511 hydrochloride is a structural analogue of LY294002. LY303511 does not inhibit PI3K.
NSC781406 Chemical Structure
 BCP20676 NSC781406 1676893-24-5
NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα.
GNE 477 Chemical Structure
 BCP07720 GNE 477 1032754-81-6
GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor
PKI-402 Chemical Structure
 BCP02609 PKI-402 1173204-81-3
PKI-402 is a selective, reversible, ATP-competitive, equipotent class I phosphatidylinositol 3-kinases (PI3K) inhibitor with IC50 of 1, 7, 16 and 14 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively.
PF04979064 Chemical Structure
 BCP06871 PF04979064 1220699-06-8
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with Kis of 0.13 nM and 1.42 nM for PI3Kα and mTOR, respectively.
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