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Raw Materials
mTOR
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP38015 | MT 63-78 New | 1179347-65-9 |
MT 63-78 is a direct activator of AMPK, and an inhibitor of prostate cancer growth by blocking lipogenesis.
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BCP36715 | MTI-31 New | 1567915-38-1 |
MTI-31 is a novel potent, selective mTORC1/mTORC2 inhibitor with Kd of 0.2 nM (mTOR), displays >5,000-fold selectivity over PIK3CA, PIK3CB and PIK3G.
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BCP36117 | PI-103 Hydrochloride New | 371935-79-4 |
PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.
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BCP33282 | Rapalink-1 New | Rapalink-1 |
RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin with MLN0128 (a second-generation mTOR kinase inhibitor) by an inert chemical linker.
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BCP25958 | AZD8055 Fumaric acid New | 1201799-05-4 |
AZD-8055 is a novel ATP-competitive inhibitor of mTOR kinase with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2.
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BCP25959 | AZD8055 D(-)-Tartaric Acid New | 1201799-04-3 |
AZD-8055 is a novel ATP-competitive inhibitor of mTOR kinase with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2.
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BCP32690 | mTOR inhibitor-1 New | 468747-17-3 |
mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy.
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BCP32612 | XL-765 New | 1123889-87-1 |
XL765 is a PI3K/mTOR dual kinase inhibitor and it is more potent compared to an agent that inhibits either PI3K kinase or mTOR kinase alone.
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BCP26216 | BGT226 New | 915020-55-2 |
BGT226 is a PI3K (with IC50s of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ)/mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells.
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BCP23427 | WYE-687 New | 1062161-90-3 |
WYE-687 is a potent and ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM.
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