Home   >  

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Jak/Stat Pathway

Chemical Structure Cat. No. Product Name CAS No.
AZD-8931 Difumaric acid Chemical Structure
BCP24789 AZD-8931 Difumaric acid 1196531-39-1
AZD-8931 is a reversible, ATP competitive EGFR inhibitor of with IC50s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively.
Baricitinib trifluoroacetate Chemical Structure
BCP16048 Baricitinib trifluoroacetate 1187594-10-0
Baricitinib, also known as INCB 028050 or LY 3009104, is an orally administered selective JAK1 andk JAK 2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK 2( 5.7 nM).
Ruxolitinib maleic acid salt Chemical Structure
BCP30121 Ruxolitinib maleic acid salt 1092939-15-5
Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3.
Ruxolitinib sulfate Chemical Structure
BCP27733 Ruxolitinib sulfate 1092939-16-6
Ruxolitinib sulfate is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3.3 nM/2.8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3.
CEP33779 Chemical Structure
BCP27756 CEP33779 1257704-57-6
CEP-33779 is a novel, selective, and orally bioavailable inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.
LGB321 Chemical Structure
BCP13641 LGB321 1210415-88-5
LGB-321 is a potent and selective ATP-competitive small molecule inhibitor of PIM kinases (Pan-PIM kinase inhibitor).
TX-1918 Chemical Structure
BCP16358 TX-1918 503473-32-3
TX-1918 is a cell-permeable tyrphostin derivative that inhibits eukaryotic elongation factor-2 kinase (eEF-2K; IC50 = 440 nM).
TP-3654 Chemical Structure
BCP30070 TP-3654 1361951-15-6
TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.
RX-518 Chemical Structure
BCP19075 RX-518 1660963-42-7
RX518 is an epidermal growth factor receptor (EGFR) inhibitor.
FM-381 Chemical Structure
BCP29350 FM-381 2226521-65-7
FM-381 is a Chemical Probe For JAK3 and JAK3 specific reversible covalent inhibitor.
123下一页末页共 193 条记录 1 / 20 页 
0086-13720134139