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Signaling Pathways
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GPCR/G Protein
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Protease/Metabolic Enzyme
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Research Areas
- Metabolic Disease
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Pyridazine Series
- Azaindazole
- Nucleoside Series
- Quinazoline
- Boric acid
- Pyrazole Series
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- Pyrimidine Series
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Benzene Series
- Pyridine Series
Raw Materials
Bcl2
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP25146 | AMG176 | 1883727-34-1 |
AMG-176 is an inhibitor of induced myeloid leukemia cell differentiation protein MCL-1 (myeloid cell leukemia-1), with potential pro-apoptotic and antineoplastic activities.
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BCP25104 | (-)BI97D6 | 1430067-36-9 |
The apogossypolone derivative -BI97D6 binds MCL1 and BCL2, BCL-XL, BFL1 with high affinities.
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BCP20986 | Sabutoclax | 1228108-65-3 |
Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively.
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BCP24040 | AT-101 acetic acid | 866541-93-7 |
Gossypol Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes such as lactate dehydrogenase, NAD-linked enzymes.
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BCP18443 | CID5721353 | 301356-95-6 |
CID5721353 is a B-Cell Lymphoma 6 Inhibitor (BCL6 inhibitor).
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BCP17018 | BDA-366 | 142645-19-0/1909226-00-1 |
BDA-366 is a small-molecule Bcl2-BH4 domain antagonist, BDA-366, that binds BH4 with high affinity and selectivity.
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BCP29223 | MIK 665 | 1799631-75-6 |
MIK665, also known as S 64315, is an inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3), with potential pro-apoptotic and antineoplastic activities.
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BCP09006 | Aceticacidgossypol | 12542-36-8 |
Gossypol, a natural product isolated from cottonseeds and roots, binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively.
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BCP17483 | BH3I-1 | 300817-68-9 |
BH3I-1 is a Bcl-2 antagonist. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair.
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BCP20471 | FX1 | 1426138-42-2 |
FX1 is a potent and specific BCL6 inhibitor, with an IC50 of around 35 μM.
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