Home   >  
Epigenetics
  >  
Histone Demethylase

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Histone Demethylase

Chemical Structure Cat. No. Product Name CAS No.
KDM5-IN-1 Chemical Structure
 BCP37630 KDM5-IN-1 1628210-26-3
KDM5-IN-1 is a potent, selective and orally bioavailable KDM5 inhibitor.
KDM5-C70 Chemical Structure
 BCP37627 KDM5-C70 1596348-32-1
KDM5-C70 is a JARID1 Histone Demethylases Inhibitor. KDM5-C70 had an antiproliferative effect in myeloma cells, leading to genome-wide elevation of H3K4me3 levels.
CC-90011 besylate Chemical Structure
 BCP33218 CC-90011 besylate 2097523-60-7
CC-90011 is a potent and orally active LSD1 inhibitor. CC-90011 binds to and inhibits LSD1, a demethylase that suppresses the expression of target genes by converting the di- and mono-methylated forms of lysine at position 4 of histone H3 (H3K4) to mono- and unmethylated H3K4, respectively.
OG-L002 hydrochloride Chemical Structure
 BCP25948 OG-L002 hydrochloride 1357298-75-9
OG-L002 HCl is an inhibitor of LSD1.
KDM4D-IN-1 Chemical Structure
 BCP32624 KDM4D-IN-1 2098902-68-0
KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.
KDOAM-25 Chemical Structure
 BCP31703 KDOAM-25 2230731-99-2
KDOAM-25 is a potent and highly selective KDM5 sub-family of histone lysine demethylases inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells.
GSK-467 Chemical Structure
 BCP30840 GSK-467 1628332-52-4
GSK467 is a potent and selective inhibitor of KDM5 (also known as JARID1). GSK467 exploits unique binding modes.
T-3775440 Chemical Structure
 BCP30535 T-3775440 1422620-34-5
T-3775440 is a novel potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM.
T-3775440 hydrochloride Chemical Structure
 BCP30534 T-3775440 hydrochloride 1422535-52-1
T-3775440 hydrochloride is a potent, selecitve, irreversible LSD1 inhibitor.
Corin Chemical Structure
 BCP30529 Corin 1808113-09-8
Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.
123下一页末页共 35 条记录 1 / 4 页 
0086-15971444841