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Histone Demethylase

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Histone Demethylase

Chemical Structure Cat. No. Product Name CAS No.
T-3775440 Chemical Structure
 BCP30535 T-3775440 1422620-34-5
T-3775440 is a novel potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM.
T-3775440 hydrochloride Chemical Structure
 BCP30534 T-3775440 hydrochloride 1422535-52-1
T-3775440 hydrochloride is a potent, selecitve, irreversible LSD1 inhibitor.
Corin Chemical Structure
 BCP30529 Corin 1808113-09-8
Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.
Trans-2-Phenylcyclopropylamine hemisulfate salt Chemical Structure
 BCP15493 Trans-2-Phenylcyclopropylamine hemisulfate salt 13492-01-8
Tranylcypromine hemisulfate is an irreversible, nonselective MAO inhibitor used in the treatment of depression.
Seclidemstat Chemical Structure
 BCP29581 Seclidemstat 1423715-37-0
Seclidemstat is an antineoplastic drug candidate.
AS-8351 Chemical Structure
 BCP29140 AS-8351 796-42-9
AS-8351 induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
KDM4B-IN-B3 Chemical Structure
 BCP29547 KDM4B-IN-B3 2003260-55-5
KDM4B-IN-B3 is a potent KDM4B inhibitor with an IC50 of 10 nM.
OG-L002 Chemical Structure
 BCP12278 OG-L002 1357302-64-7
OG-L002 is a potent LSD1 inhibitor that has been found to inhibit herpes simplex virus (HSV) immediate early gene expression and viral yield in vitro and suppresses HSV primary infection in vivo.
Vafidemstat Chemical Structure
 BCP29383 Vafidemstat 1357362-02-7
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1) inhibitor.
RN-1 Chemical Structure
 BCP20812 RN-1 1781835-13-9
Potent lysine specific demethylase 1 (LSD1) inhibitor (IC50 = 70 nM). Exhibits selectivity for LSD1 over MAO-A and MAO-B (IC50 values are 0.51 and 2.79 μM for MAO-A and MAO-B, respectively). Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration.
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