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Histone Demethylase

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Histone Demethylase

Chemical Structure Cat. No. Product Name CAS No.
GSK-467 Chemical Structure
BCP30840 GSK-467 1628332-52-4
GSK467 is a potent and selective inhibitor of KDM5 (also known as JARID1). GSK467 exploits unique binding modes.
T-3775440 Chemical Structure
BCP30535 T-3775440 1422620-34-5
T-3775440 is a novel potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM.
T-3775440 hydrochloride Chemical Structure
BCP30534 T-3775440 hydrochloride 1422535-52-1
T-3775440 hydrochloride is a potent, selecitve, irreversible LSD1 inhibitor.
Corin Chemical Structure
BCP30529 Corin 1808113-09-8
Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.
Tranylcypromine hemisulfate Chemical Structure
BCP15493 Tranylcypromine hemisulfate 13492-01-8
Tranylcypromine hemisulfate is an irreversible, nonselective MAO inhibitor used in the treatment of depression.
Seclidemstat Chemical Structure
BCP29581 Seclidemstat 1423715-37-0
Seclidemstat is an antineoplastic drug candidate.
AS-8351 Chemical Structure
BCP29140 AS-8351 796-42-9
AS-8351 induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
KDM4B-IN-B3 Chemical Structure
BCP29547 KDM4B-IN-B3 2003260-55-5
KDM4B-IN-B3 is a potent KDM4B inhibitor with an IC50 of 10 nM.
OG-L002 Chemical Structure
BCP12278 OG-L002 1357302-64-7
OG-L002 is a potent LSD1 inhibitor that has been found to inhibit herpes simplex virus (HSV) immediate early gene expression and viral yield in vitro and suppresses HSV primary infection in vivo.
Vafidemstat Chemical Structure
BCP29383 Vafidemstat 1357362-02-7
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1) inhibitor.
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