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MEK/ERK

Chemical Structure Cat. No. Product Name CAS No.
TMCB Chemical Structure
BCP27716 TMCB 905105-89-7
TMCB is a dual-kinase inhibitor. It acts by inhibiting both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8).
D-87503 Chemical Structure
BCP27634 D-87503 800394-83-6
D-87503 is a dual extracellular signaling-related kinase (ERK)/PI3K inhibitor.
CC-90003 Chemical Structure
BCP23624 CC-90003 1621999-82-3
CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.
MK-8353 Chemical Structure
BCP23615 MK-8353 1184173-73-6
MK-8353 is a potent, selective and orally available ERK1/2 inhibitor, with IC50s of 23.0 nM and 8.8 nM, respectively; MK-8353 has antitumor activity.
Ulixertinib hydrochloride Chemical Structure
BCP30834 Ulixertinib hydrochloride 1956366-10-1
Ulixertinib hydrochloride is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.
Sodium Taurodeoxycholate Chemical Structure
BCP16412 Sodium Taurodeoxycholate 1180-95-6
Sodium taurodeoxycholate is a bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.
Tauroursodeoxycholic acid sodium salt Chemical Structure
BCP14861 Tauroursodeoxycholic acid sodium salt 35807-85-3
Tauroursodeoxycholate Sodium is an ambiphilic bile acid that helps with liver and gallbladder issues.
LM22B-10 Chemical Structure
BCP30139 LM22B-10 342777-54-2
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
KO947 HCl Chemical Structure
BCP29926 KO947 HCl KO947HCL
KO-947 is a potent and selective ERK inhibitor with slow dissociation kinetics.
FR 180204 Chemical Structure
BCP09857 FR 180204 865362-74-9
FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively.
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