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Casein Kinase

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Casein Kinase

Chemical Structure Cat. No. Product Name CAS No.
CK1-IN-1 Chemical Structure
BCP35045 CK1-IN-1 1784751-20-7
CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively.
Longdaysin Chemical Structure
BCP32583 Longdaysin 1353867-91-0
Longdaysin is a novel inhibitor of CK1, ERK2, and CDK7 kinases.
BioE-1115 Chemical Structure
BCP32544 BioE-1115 1268863-35-9
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE-1115 is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM.
TMCB Chemical Structure
BCP27716 TMCB 905105-89-7
TMCB is a dual-kinase inhibitor. It acts by inhibiting both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8).
NCC007 Chemical Structure
BCP30832 NCC007 NCC007
NCC007 is a novel CKIα and CKIδ dual inhibitor.
PF-5006739 Chemical Structure
BCP29752 PF-5006739 1293395-67-1
PF-5006739 is a potent casesin kinase 1δ/ε inhibitor (IC50 values are 3.9 and 17 nM, respectively). Mediates circadian rhythm phase-delaying effects in vivo. Attenuates opioid drug seeking behaviour in addiction in vivo models.
PF4800567 Chemical Structure
BCP28458 PF4800567 1188296-52-7
PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.
TA-01 Chemical Structure
BCP24229 TA-01 1784751-18-3
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.
Ellagic acid Chemical Structure
BCP10830 Ellagic acid 476-66-4
Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM.
IC 261 Chemical Structure
BCP16652 IC 261 186611-52-9
IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) that inhibits Ckiδ and Ckiε (IC50 = ~1 μM for both), as well as CK1α (IC50 = 16 μM).
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