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URAT1

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URAT1

Chemical Structure Cat. No. Product Name CAS No.
JTT-552 Chemical Structure
BCP21027 JTT-552 888730-46-9
JTT-552 is a uric acid transporter 1 (URAT1) inhibitor potentially for the treatment of hyperuricemia.
Verinurad Chemical Structure
BCP17058 Verinurad 1352792-74-5
Verinurad is an urate transporter inhibitor with EC50 value of 0.05 μM.
RDEA594 Chemical Structure
BCP06435 RDEA594 878672-00-5
Lesinurad, once-daily inhibitor of URAT1, is a transporter in the kidney that regulates uric acid excretion from the body.
Lesinurad sodium Chemical Structure
BCP11514 Lesinurad sodium 1151516-14-1
Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 µM, respectively.
UR 1102 Chemical Structure
BCP30414 UR 1102 1198153-15-9
UR 1102 is an inhibitor of the renal urate transporter URAT1. UR 1102 effectively increases the fractional excretion of urinary uric acid, and reduces plasma uric acid. It is promisingly used as a therapeutic for gout or hyperuricemia with an enhanced pharmacokinetic profile.
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