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Chemical Structure Cat. No. Product Name CAS No.
ABC-1183 Chemical Structure
BCP30547 ABC-1183 1042735-18-1
ABC-1183 is a selective dual GSK3α/β and CKD9 inhibitor.
BIO-acetoxime Chemical Structure
BCP27976 BIO-acetoxime 667463-85-6
BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity.
CHIR-99021 HCl Chemical Structure
BCP26126 CHIR-99021 HCl 1797989-42-4
CHIR-99021 HCl is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2.
2-D08 Chemical Structure
BCP18314 2-D08 144707-18-6
2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation.
GSK-3 INHIBITOR XIII Chemical Structure
BCP12434 GSK-3 INHIBITOR XIII 404828-08-6
GSK-3 Inhibitor XIII is an aminopyrazole compound that acts as an ATP-binding site inhibitor of GSK-3.
ZSTK474 Chemical Structure
BCP01867 ZSTK474 475110-96-4
ZSTK474 is an ATP-competitive pan-class I PI3K inhibitor with IC50s of16 nM, 44 nM, 4.6 nM and 49 nM for PΙ3Κα, PI3Kβ, PI3Kδ and PI3Kγ, respectively.
Indirubin Chemical Structure
BCP02284 Indirubin 479-41-4;906748-38-7
Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 75 nM and 0.19 μM.
GF109203X Chemical Structure
BCP08311 GF109203X 133052-90-1
GF109203X is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor.
NVP-ADW742 Chemical Structure
BCP27617 NVP-ADW742 475488-23-4
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
TDZD-8 Chemical Structure
BCP07657 TDZD-8 327036-89-5
TDZD-8 is a selective inhibitor of GSK-3, a thiadiazolidinone derivative, non-ATP competitive inhibitor of GSK-3β (IC50 = 2 μM).
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