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DHFR

Chemical Structure Cat. No. Product Name CAS No.
(+/-)Amethopterin Chemical Structure
BCP29918 (+/-)Amethopterin 60388-53-6
Amethopterin is a chemotherapy agent and immune system suppressant.
Calcium levofolinate Chemical Structure
BCP06607 Calcium levofolinate 80433-71-2
Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.
5-Methyltetrahydrofolate calcium Chemical Structure
BCP29923 5-Methyltetrahydrofolate calcium 26560-38-3
Calcium N5-methyltetrahydrofolate(NSC173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.
Levomefolic Acid Chemical Structure
BCP29924 Levomefolic Acid 31690-09-2
Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
Abitrexate Chemical Structure
BCP02078 Abitrexate 59-05-2
Methotrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.
Methotrexate hydrate Chemical Structure
BCP13701 Methotrexate hydrate 133073-73-1
Methotrexate ,analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells.
Methotrexate disodium salt Chemical Structure
BCP13700 Methotrexate disodium salt 7413-34-5
Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells.
D-Pemetrexed Hydrate Chemical Structure
BCP07120 D-Pemetrexed Hydrate 937370-10-0
Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
Pemetrexed disodium hydrate Chemical Structure
BCP22709 Pemetrexed disodium hydrate 357166-30-4
Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
Pemetrexed disodium Chemical Structure
BCP23433 Pemetrexed disodium 150399-23-8
Pemetrexed disodium is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
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