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mGluR

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mGluR

Chemical Structure Cat. No. Product Name CAS No.
AIDA Chemical Structure
BCP49140 AIDA 168560-79-0
AIDA, a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis.
Dipraglurant Chemical Structure
BCP23706 Dipraglurant 872363-17-2
Dipraglurant is a potent, selective, orally active and brain penetrant mGluR5 negative allosteric modulator (NAM), with an IC50 of 21 nM. Dipraglurant can reduce Levodopa-induced dyskinesia (LID) in vivo.
MMPIP Chemical Structure
BCP23933 MMPIP 479077-02-6
MMPIP is an allosteric metabotropic glutamate receptor 7 (mGluR7) selective antagonist (KB values 24 -30 nM).
VU0364289 Chemical Structure
BCP23956 VU0364289 1242443-29-3
VU0364289 is a novel N-aryl piperazine mGlu5 positive allosteric modulator.
Rapastinel acetate Chemical Structure
BCP24900 Rapastinel acetate 491872-39-0
Rapastinel is a novel antidepressant drug approved as an adjunctive therapy for the treatment of treatment-resistant major depressive disorder.
Rapastinel Trifluoroacetate Chemical Structure
BCP24901 Rapastinel Trifluoroacetate 1435786-04-1
Rapastinel Trifluoroacetate is an NMDA receptor modulator with glycine-site partial agonist properties.
3-MATIDA Chemical Structure
BCP24974 3-MATIDA 518357-51-2
3-MATIDA is a metabotropic glutamate I (mGlu1) receptor antagonist.
DMeOB Chemical Structure
BCP48798 DMeOB 40252-74-2
DMEOB is a negative allosteric modulator at the metabotropic glutamate receptor mGluR5.
WAY-324099 Chemical Structure
BCP48088 WAY-324099 374548-18-2
WAY-324099 is a modulator of mGluR3; altering the lifespan of a eukaryotic organism.
LY2979165 Chemical Structure
BCP44009 LY2979165 1311385-35-9
LY-2979165 is a metabotropic glutamate receptor agonist prodrug.
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