Home   >  
Neuro Signaling Pathway
  • GPCR/G Protein
∨
  >  
mGluR

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

mGluR

Chemical Structure Cat. No. Product Name CAS No.
YM 298198 Hydrochloride Chemical Structure
 BCP33084 YM 298198 Hydrochloride 748758-45-4
YM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM).
NPS 2390 Chemical Structure
 BCP33083 NPS 2390 226878-01-9
NPS2390 is a group I mGlu antagonist; displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors.
SIB 1893 Chemical Structure
 BCP33034 SIB 1893 6266-99-5
SIB-1893 is a selective non-competitive antagonist of the metabotropic glutamate mGlu5 receptor subtype.
SIB 1757 Chemical Structure
 BCP33033 SIB 1757 31993-01-8
SIB-1757 is a highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype. SIB-1757 displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
GET-73 Chemical Structure
 BCP32664 GET-73 202402-01-5
GET-73 is a mGlu5 receptor allosteric modulator potentially for the treatment of alcoholism.
ADX-88178 Chemical Structure
 BCP32622 ADX-88178 1235318-89-4
ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4.
PHCCC Chemical Structure
 BCP25038 PHCCC 179068-02-1
PHCCC is a Group I metabotropic glutamate receptor antagonist with EC 50 of 6 uM and a positive allosteric modulator of mGluR4. Also as a potent to antagonism for mGluR2 and mGluR8.
Eglumetad Chemical Structure
 BCP21205 Eglumetad 176199-48-7
Eglumegad is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively.
VU-29 Chemical Structure
 BCP27694 VU-29 890764-36-0
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); binds to the MPEP allosteric site (Ki app = 244 nM).
FITM Chemical Structure
 BCP30765 FITM 932737-65-0
FITM is a potent mGlu1 inhibitor.
123下一页末页共 43 条记录 1 / 5 页 
0086-15971444841