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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
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Raw Materials
mGluR
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP38019 | VU0155094 New | 731006-86-3 |
VU0155094 is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively.
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BCP37624 | AZD-8529 mesylate New | 1314217-69-0 |
AZD-8529 mesylate is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
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BCP37625 | AZD-8529 New | 1092453-15-0 |
AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.
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BCP33908 | Decoglurant New | 911115-16-7 |
Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant.
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BCP33084 | YM 298198 Hydrochloride New | 748758-45-4 |
YM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM).
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BCP33083 | NPS 2390 New | 226878-01-9 |
NPS2390 is a group I mGlu antagonist; displays noncompetitive antagonist activity at both mGlu1 and mGlu5 receptors.
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BCP33034 | SIB 1893 New | 6266-99-5 |
SIB-1893 is a selective non-competitive antagonist of the metabotropic glutamate mGlu5 receptor subtype.
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BCP33033 | SIB 1757 New | 31993-01-8 |
SIB-1757 is a highly selective antagonist for the mGlu5 metabotropic glutamate receptor subtype. SIB-1757 displays an IC50 value of 0.4 μM at hmGlu5 compared with > 30 μM at hmGlu1b, hmGlu2, hmGlu4, hmGlu6, hmGlu7 and hmGlu8.
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BCP32664 | GET-73 New | 202402-01-5 |
GET-73 is a mGlu5 receptor allosteric modulator potentially for the treatment of alcoholism.
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BCP32622 | ADX-88178 New | 1235318-89-4 |
ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4.
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