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Keap1 Nrf2

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Keap1 Nrf2

Chemical Structure Cat. No. Product Name CAS No.
4-Octyl Itaconate Chemical Structure
BCP31060 4-Octyl Itaconate 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Ezetimibe Ketone Chemical Structure
BCP09273 Ezetimibe Ketone 191330-56-0
Ezetimibe Ketone is Phase-I metabolite of Ezetimibe.
DH404 Chemical Structure
BCP30092 DH404 DH404
Dihydro-CDDO-trifluoroethyl amide (dh404) is a novel Nrf2 activator and suppresses oxidative stress in cardiomyocytes.
K67 Chemical Structure
BCP26006 K67 2046250-48-8
K67 is a specific inhibitor of the interaction between S349-phosphorylated p62 and Keap1, exhibts no inhibitory effect on the interaction of full-length Keap1 with Nrf2-ETGE or full-length Nrf2.
Dl-sulforaphane Chemical Structure
BCP19599 Dl-sulforaphane 4478-93-7
Sulforaphane is an inducer of chemopreventative enzymes via Keap1-Nrf2 signaling. Sulforaphane is present naturally in widely consumed vegetables and has a particularly high concentration in broc-coli.
Eriodictyol Chemical Structure
BCP13401 Eriodictyol 552-58-9
Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity.
Pyridoxine Chemical Structure
BCP27975 Pyridoxine 65-23-6
Pyridoxine is a pyridine derivative.
Mangiferin Chemical Structure
BCP28352 Mangiferin 4773-96-0
Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50.
NSC172924 Chemical Structure
BCP15272 NSC172924 14907-98-3
Danshensu Chemical Structure
BCP28285 Danshensu 76822-21-4
Danshensu, a herbal preparation used in traditional Chinese medicine, possesses potential antitumor and anti‑angiogenesis effects.
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