Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Somatostatin Receptor
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Adenosine Receptor
- Glucagon Receptor
- Prostaglandin Receptor
- NK Receptor
- GnRH Receptor
- Leukotriene Receptor
- Glucocorticoid Receptor
- CGRP Receptor
- GPR
- P2 Receptor
- mAChR
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Vasopressin Receptor
- Smoothened/Smo
- Opioid Receptor
- mGluR
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- CGRP Receptor
- FAAH
- P2 Receptor
- nAChR
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- Carboxypeptidase
- 11β HSD
- Xanthine Oxidase
- ACC
- Mitochondrial Metabolism
- Pyruvate Kinase
- ALDH
- SCD
- Serine Protease
- CETP
- Neprilysin
- FTase
- MAGL
- MLR
- Carbonic Anhydrase
- ROR
- NOX
- PAI1
- Elastase
- E1 E2 E3 Enzyme
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HSP
- HCV Protease
- Tryptophan Hydroxylase/TPH
- DPP
- Factor Xa
- Procollagen C Proteinase
- Integrase
- Phospholipase
- Phosphodiesterase/PDE
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Infection
- Inflammation
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Azaindazole
- Pyridazine Series
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrimidine Series
- Boric acid
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Piperidine Series
- Indole Series
- Indazole Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
LRRK2
Chemical Structure | Cat. No. | Product Name | CAS No. |
---|
![]() |
BCP30270 | PF-06454589 New | 1527473-30-8 |
PF-06454589 is a potent and selective LRRK2 inhibitor.
|
![]() |
BCP09654 | GNE-0877 | 1374828-69-9 |
GNE0877 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitor with an IC50 of 3 nM.
|
![]() |
BCP15148 | CZC-54252 | 1191911-27-9 |
CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.
|
![]() |
BCP09557 | CZC-25146.HCl | 1330003-04-7 |
CZC-25146 Hcl is a potent, selective and metabolically stable LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively.
|
![]() |
BCP14116 | CZC 25146 | 1191911-26-8 |
CZC-25146 is a potent, selective and metabolically stable LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively.
|
![]() |
BCP09106 | HG-10-102-01 | 1351758-81-0 |
HG-10-102-01 is a brain penetrant, potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant (IC50 for LRRK2-wild-type ~20.3 nM and LRRK2-[G2019S] ~3.2 nM).
|
![]() |
BCP10209 | GNE9605 | 1536200-31-3 |
GNE-9605 is a highly potent, selective, and brain-penetrant LRRK2 inhibitor with IC50 of 19 nM.
|
![]() |
BCP07701 | GSK2578215A | 1285515-21-0 |
GSK257821A is a potent inhibitor of leucine-rich repeat kinase-2 (LRRK2).
|
![]() |
BCP09873 | GNE7915 | 1351761-44-8 |
GNE-7915 is a highly potent, selective, and brain-penetrable LRRK2 small molecule inhibitor with IC50 of 9 nM in cellular LRRK2 assay; > 100 fold selectivity against a panel of 187 kianses(Ki).
|
![]() |
BCP23651 | GNE-7915 tosylate | GNE-7915tosylate |
GNE-7915 tosylate is a potent, selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM.
|
