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Chemical Structure Cat. No. Product Name CAS No.
CC-90009 Chemical Structure
BCP33889 CC-90009 1860875-51-9
CC-90009 is a cereblon (CRBN) E3 ligase modulator. Cereblon modulator 1 specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex. This leads to the ubiquitination of certain substrate proteins and induces the proteasome-mediated degradation of certain transcription factors, including Ikaros (IKZF1) and Aiolos (IKZF3).
LC3-mHTT-IN-AN1 Chemical Structure
BCP33879 LC3-mHTT-IN-AN1 486443-73-6
LC3-mHTT-IN-AN1 is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins.
NS-3-008 hydrochloride Chemical Structure
BCP33849 NS-3-008 hydrochloride 1172854-54-4
NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease.
Omaveloxolone Chemical Structure
BCP28609 Omaveloxolone 1474034-05-3
Omaveloxolone, also known as RTA-408, is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity.
MN58b Chemical Structure
BCP33830 MN58b 203192-01-2
MN58b is a selective choline kinase α (CHKα) inhibitor, and results in inhibition of phosphocholine synthesis. MN58b reduces cell growth through the induction of apoptosis, and also has antitumoral activity.
Avacopan Chemical Structure
BCP33812 Avacopan 1346623-17-3
Avacopan blocked the C5a binding, C5a-mediated migration, calcium mobilization, and CD11b upregulation in U937 cells as well as in freshly isolated human neutrophils.
LR-90 Chemical Structure
BCP33770 LR-90 245075-84-7
LR-90 is an advanced glycation end product (AGE) inhibitor, inhibits inflammatory responses in human monocytes.
TH5487 Chemical Structure
BCP33761 TH5487 2304947-71-3
TH 5487 is a selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor.
Galanin (1-19) (human) Chemical Structure
BCP33739 Galanin (1-19) (human) 136005-51-1
Tisocalcitate Chemical Structure
BCP33666 Tisocalcitate 156965-06-9
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