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TRP Channel

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TRP Channel

Chemical Structure Cat. No. Product Name CAS No.
L-Menthol Chemical Structure
 BCP27552 L-Menthol 2216-51-5
Levomenthol is a key component of peppermint oil that binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, to increase [Ca2+]i. Antitumor activity.
ABT-102 Chemical Structure
 BCP27708 ABT-102 808756-71-0
ABT 102 is a selective transient receptor potential vanilloid 1 (TRPV1) receptor antagonist with IC50 values to be 5-7 nM.
N-(p-amylcinnamoyl) Anthranilic Acid Chemical Structure
 BCP30845 N-(p-amylcinnamoyl) Anthranilic Acid 110683-10-8
N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. N-(p-amylcinnamoyl) Anthranilic Acid (ACA) is also an effective reversible inhibitor of calcium-activated chloride channels, has potential to treat arrhythmia.
AMG-333 Chemical Structure
 BCP30858 AMG-333 1416799-28-4
AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.
Elismetrep Chemical Structure
 BCP30294 Elismetrep 1400699-64-0
Elismetrep is a non-opioid analgesic drug candidate.
SAR7334 Chemical Structure
 BCP11028 SAR7334 1333210-07-3
SAR7334 is a potent TRPC6 (Transient receptor potential cation channel, subfamily C, member 6) inhibitor.
Icilin Chemical Structure
 BCP27818 Icilin 36945-98-9
Icilin(AG 3-5) is a synthetic super-agonist of TRPM8 ion channel.
HC-070 Chemical Structure
 BCP29966 HC-070 1628291-95-1
HC-070 is a potent inhibitor of TRPC4 and TRPC5, leading to anxiolytic and antidepressant effects in mice.
ML 204 Chemical Structure
 BCP28617 ML 204 5465-86-1
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
TRPM8 antagonist 14 Chemical Structure
 BCP29863 TRPM8 antagonist 14 259674-19-6
TRPM8 antagonist 14 is a potent, selective TRPM8 antagonist with IC50 of 0.2 nM in calcium influx assays, shows no activity on TRPV1; shows significant target coverage in both an icilin-induced WDS (at 1-30 mg/kg s.c.) and oxaliplatin-induced cold allodynia (at 0.1-1 μg s.c.) mice models.
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