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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
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Raw Materials
TRP Channel
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP11028 | SAR7334 New | 1333210-07-3 |
SAR7334 is a potent TRPC6 (Transient receptor potential cation channel, subfamily C, member 6) inhibitor.
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BCP27818 | Icilin New | 36945-98-9 |
Icilin(AG 3-5) is a synthetic super-agonist of TRPM8 ion channel.
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BCP29966 | HC-070 New | 1628291-95-1 |
HC-070 is a potent inhibitor of TRPC4 and TRPC5, leading to anxiolytic and antidepressant effects in mice.
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BCP28617 | ML 204 | 5465-86-1 |
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
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BCP29863 | TRPM8 antagonist 14 | 259674-19-6 |
TRPM8 antagonist 14 is a potent, selective TRPM8 antagonist with IC50 of 0.2 nM in calcium influx assays, shows no activity on TRPV1; shows significant target coverage in both an icilin-induced WDS (at 1-30 mg/kg s.c.) and oxaliplatin-induced cold allodynia (at 0.1-1 μg s.c.) mice models.
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BCP21785 | Probenecid | 57-66-9 |
Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels.
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BCP28444 | Rosiglitazone hydrochloride | 302543-62-0 |
Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
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BCP28340 | SAR7334 hydrochloride | 1333207-63-8 |
SAR7334 hydrochloride is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM.
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BCP23936 | Mavatrep | 956274-94-5 |
Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6.
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BCP09851 | Dihydrocapsaicin | 19408-84-5 |
Dihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers (Capsicum).
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