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TRP Channel

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TRP Channel

Chemical Structure Cat. No. Product Name CAS No.
Elismetrep Chemical Structure
 BCP30294 Elismetrep 1400699-64-0
Elismetrep is a non-opioid analgesic drug candidate.
SAR7334 Chemical Structure
 BCP11028 SAR7334 1333210-07-3
SAR7334 is a potent TRPC6 (Transient receptor potential cation channel, subfamily C, member 6) inhibitor.
Icilin Chemical Structure
 BCP27818 Icilin 36945-98-9
Icilin(AG 3-5) is a synthetic super-agonist of TRPM8 ion channel.
HC-070 Chemical Structure
 BCP29966 HC-070 1628291-95-1
HC-070 is a potent inhibitor of TRPC4 and TRPC5, leading to anxiolytic and antidepressant effects in mice.
ML 204 Chemical Structure
 BCP28617 ML 204 5465-86-1
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
TRPM8 antagonist 14 Chemical Structure
 BCP29863 TRPM8 antagonist 14 259674-19-6
TRPM8 antagonist 14 is a potent, selective TRPM8 antagonist with IC50 of 0.2 nM in calcium influx assays, shows no activity on TRPV1; shows significant target coverage in both an icilin-induced WDS (at 1-30 mg/kg s.c.) and oxaliplatin-induced cold allodynia (at 0.1-1 μg s.c.) mice models.
Probenecid Chemical Structure
 BCP21785 Probenecid 57-66-9
Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels.
Rosiglitazone hydrochloride Chemical Structure
 BCP28444 Rosiglitazone hydrochloride 302543-62-0
Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
SAR7334 hydrochloride Chemical Structure
 BCP28340 SAR7334 hydrochloride 1333207-63-8
SAR7334 hydrochloride is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM.
Mavatrep Chemical Structure
 BCP23936 Mavatrep 956274-94-5
Mavatrep is an orally bioavailable TRPV1 antagonist (Ki=6.5 nM), exhibits minimal effect on the enzymatic activity (IC50 > 25 μM) of CYP isoforms 3A4, 1A2, and 2D6.
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