Home   >  
Epigenetics
  >  
Epigenetic Reader Domain

Classified by application

All Products

Signaling Pathways

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Epigenetic Reader Domain

Chemical Structure Cat. No. Product Name CAS No.
M-89 Chemical Structure
 BCP35588 M-89 2363165-42-6
M-89 is a highly potent and specific menin inhibitor, with a Kd of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia.
Y06036 Chemical Structure
 BCP35043 Y06036 1832671-96-1
Y06036 is a potent and selective BET inhibitor, which binds to the BRD4(1) bromodomain with Kd value of 82 nM. Antitumor activity.
MS31 Chemical Structure
 BCP34903 MS31 2366264-12-0
MS31 is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 potently inhibits the interactions between SPIN1 and H3K4me3. It is not toxic to nontumorigenic cells.
VTP-50469 Chemical Structure
 BCP34837 VTP-50469 2169916-18-9
VTP50469 is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a Ki of 104 pM. VTP50469 has potently anti-leukemia activity.
Alobresib Chemical Structure
 BCP33313 Alobresib 1637771-14-2
Alobresib is an antineoplastic drug candidate.
UNC-926 Hydochloride Chemical Structure
 BCP25396 UNC-926 Hydochloride 1782573-49-2
UNC-926 is a methyl-lysine (Kme) reader domain inhibitor; inhibits L3MBTL1 with an IC50 of 3.9 μM.
BETd-260 Chemical Structure
 BCP33276 BETd-260 2093388-62-4
BETd-260 is a potent BET degrader based on PROTAC technology, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line.
PF-CBP1 Chemical Structure
 BCP32782 PF-CBP1 1962928-21-7
PF-CBP1 is potent and highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) that down regulates targets of CBP in macrophages primary neurons.
A1874 Chemical Structure
 BCP32647 A1874 2064292-12-0
A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells.
dBET57 Chemical Structure
 BCP32540 dBET57 1883863-52-2
dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2.
123下一页末页共 103 条记录 1 / 11 页 
0086-15971444841