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MAGL

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MAGL

Chemical Structure Cat. No. Product Name CAS No.
DO-264 Chemical Structure
BCP31625 DO-264 2301866-59-9
DO264 is a novel ABHD12 inhibitor.
URB602 Chemical Structure
BCP19101 URB602 565460-15-3
URB602 is a selective monoacylglycerol lipase (MAGL) inhibitor, which inhibits rat brain MGL with IC50 of 28±4 μM through a noncompetitive mechanism.
ABX-1431 Chemical Structure
BCP29967 ABX-1431 1446817-84-0
ABX-1431 (ABX1431) is a highly potent, selective, orally available, CNS-penetrant monoacylglycerol lipase (MGLL) with IC50 of 14 nM (hMGLL).
KML29 Chemical Structure
BCP16466 KML29 1380424-42-9
KML29 is a potent and selective MAGL inhibitor with IC50 = 5.9, 15, and 43 nM in human, mouse, and rat brain proteomes, respectively.
JZL195 Chemical Structure
BCP23894 JZL195 1210004-12-8
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and 19 nM for mouse brain FAAH and MAGL respectively.
JZL-184 Chemical Structure
BCP28334 JZL-184 1101854-58-3
JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 μM for inhibition of MAGL and FAAH in mouse brain membranes respectively.
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