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MAPK Pathway

Chemical Structure Cat. No. Product Name CAS No.
Lifirafenib Chemical Structure
 BCP42783 Lifirafenib 1446090-79-4
Lifirafenib is a Novel potent and selective RAF Kinase and EGFR inhibitor.
MK2 Inhibitor III Chemical Structure
 BCP41255 MK2 Inhibitor III 724711-21-1
MK2 Inhibitor III is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis.
PF 3644022 Chemical Structure
 BCP40723 PF 3644022 1276121-88-0
PF 3644022 is a potent freely reversible ATP-competitive compound that inhibits MK2 activity (IC50 = 5.2 nM; Ki = 3 nM) with good selectivity when profiled against 200 human kinases.
CC-90001 Chemical Structure
 BCP38621 CC-90001 1403859-14-2
CC-90001 is a potent and selective JNK inhibitor, which is 12.9-fold more potent for JNK1 inhibition than JNK2 in a cell-based model.
BAY-885 Chemical Structure
 BCP34724 BAY-885 2307249-33-6
BAY-885 is a highly potent and selective ERK5 inhibitor.
Rineterkib Chemical Structure
 BCP38204 Rineterkib 1715025-32-3
Rineterkib is a RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway.
AZD7624 Chemical Structure
 BCP37429 AZD7624 1095004-78-6
AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
trans-Zeatin Hydrochloride Chemical Structure
 BCP36686 trans-Zeatin Hydrochloride 6025-81-6
trans-Zeatin Hydrochloride can be used in biological study and therapeutic use for plant-growth factors as cell-proliferating agents for promotion of wound healing.
TOPK inhibitor-1 Hydrochloride Chemical Structure
 BCP24278 TOPK inhibitor-1 Hydrochloride 1338545-01-9
TOPK inhibitor-1 HCl is a novel PDZ binding kinase (PBK) inhibitor.
GNE-495 Chemical Structure
 BCP36075 GNE-495 1449277-10-4
GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.
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