Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Neurotensin Receptor
- Melatonin Receptor
- Urotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Somatostatin Receptor
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- Adenosine Receptor
- OX Receptor
- Glucagon Receptor
- Prostaglandin Receptor
- NK Receptor
- GnRH Receptor
- GPR
- P2 Receptor
- mAChR
- Glucocorticoid Receptor
- Leukotriene Receptor
- CGRP Receptor
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Vasopressin Receptor
- Smoothened/Smo
- mGluR
- Opioid Receptor
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Monoamine Oxidase
- Imidazoline Receptor
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- Adrenergic Receptor
- mGluR
- Histamine Receptor
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- FAAH
- CGRP Receptor
- nAChR
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- Xanthine Oxidase
- ACC
- Mitochondrial Metabolism
- Pyruvate Kinase
- SCD
- ALDH
- Serine Protease
- Neprilysin
- CETP
- FTase
- Carbonic Anhydrase
- MAGL
- MLR
- E1 E2 E3 Enzyme
- Elastase
- PAI1
- NOX
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HCV Protease
- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- LXR
- Phosphodiesterase/PDE
- Phospholipase
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Pyridazine Series
- Azaindazole
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Quinoline Series
- Pyrimidine Series
- Thiophene Series
- Boric acid
- Pyrrole Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Pyridine Series
- Benzene Series
Raw Materials
MAPK Pathway
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP31359 | GW284543 New | 790186-68-4 |
GW284543 is a potent and selective MEK5 inhibitor with the potential for cancer treatment.
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BCP31233 | Belvarafenib New | 1446113-23-0 |
Belvarafenib is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.
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BCP21457 | SL 0101-1 New | 77307-50-7 |
SL0101 is a highly specific RSK inhibitor. SL0101 showed improved in vitro biological stability while maintaining specificity for RSK. These results should facilitate the development of RSK inhibitors derived from SL0101 as anticancer agents.
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BCP21395 | TAK1/MAP4K2 inhibitor 1 New | 1315330-11-0 |
TAK1/MAP4K2 inhibitor 1 is a B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases.
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BCP21374 | Methylthiouracil New | 56-04-2 |
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
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BCP21067 | RO5126766 New | 946128-88-7 |
Ro 5126766 is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively).
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BCP27716 | TMCB New | 905105-89-7 |
TMCB is a dual-kinase inhibitor. It acts by inhibiting both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8).
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BCP27665 | LY2322600 New | 862505-01-9 |
LY2228820 is a novel and potent p38MAPK inhibitor.
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BCP27634 | D-87503 New | 800394-83-6 |
D-87503 is a dual extracellular signaling-related kinase (ERK)/PI3K inhibitor.
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BCP23624 | CC-90003 New | 1621999-82-3 |
CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity.
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