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PAR

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PAR

Chemical Structure Cat. No. Product Name CAS No.
AC-264613 Chemical Structure
BCP25509 AC-264613 1051487-82-1
AC-264613 is a novel potent, selective protease-activated receptor PAR2 agonist with potencies ranging from 30-100 nM.
Atopaxar Chemical Structure
BCP05973 Atopaxar 751475-53-3;943239-67-6
Atopaxar, also known as E5555, is a potent and orally-active PAR-1 inhibitor.
Atopaxar hydrobromide Chemical Structure
BCP25405 Atopaxar hydrobromide 474550-69-1
Atopaxar hydrobromide is a potent, reversible PAR-1 antagonist with IC50 of 19 nM.
AZ 3451 Chemical Structure
BCP29277 AZ 3451 2100284-59-9
AZ 3451 is a potent, and selective PAR2 antagonist with Kd of 13.5 nM; shows excellent selectivity over PAR1 and PAR4 (>50 uM).
ML 161 Chemical Structure
BCP08413 ML 161 423735-93-7
ML-161 is an allosteric inhibitor of PAR1.
FR171113 Chemical Structure
BCP18806 FR171113 173904-50-2
FR 171113 is a protease-activated receptor 1 (PAR1) antagonist displaying significant antiplatelet activity in vitro.
AC55541 Chemical Structure
BCP10730 AC55541 916170-19-9
AC 55541 is a potent agonist of PAR2 with pEC50 value of 6.7 and functions range from 200 to 1000 nM .
Vorapaxar Chemical Structure
BCP08286 Vorapaxar 618385-01-6
Vorapaxar, also known as SCH 530348, is a thrombin receptor (protease-activated receptor, PAR-1) antagonist based on the natural product himbacine.
Vorapaxar Sulfate Chemical Structure
BCP12318 Vorapaxar Sulfate 705260-08-8
Vorapaxar, also known as SCH 530348, is a thrombin receptor (protease-activated receptor, PAR-1) antagonist based on the natural product himbacine.
RWJ-58259 Chemical Structure
BCP18032 RWJ-58259 315203-31-7
RWJ-58259 is a potent and selective inhibitor of PAR-1 identified as part of a synthetic chemistry program based upon a de novo design approach.
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