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Microtubule

Chemical Structure Cat. No. Product Name CAS No.
Flubendazole Chemical Structure
 BCP34258 Flubendazole 31430-15-6
Flubendazole is a safe and efficacious anthelmintic drug, which is widely used for anthelmintic to human, rodents and ruminants. Flubendazole exerts anticancer activities by mechanisms including inhibition of microtubule function. Flubendazole induces p53-mediated apoptosis and arrests G2/M cell cycle.
Indibulin Chemical Structure
 BCP33949 Indibulin 204205-90-3
Indibulin, an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis.
Vc-MMAD Chemical Structure
 BCP32929 Vc-MMAD 1401963-17-4
Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD). Vc-MMAD is a drug-linker conjugate for ADC.
VAL-CIT-PAB-MMAD Chemical Structure
 BCP32931 VAL-CIT-PAB-MMAD 1415329-13-3
VAL-CIT-PAB-MMAD is a drug-linker conjugate for ADC with potent antitumor activity by using Monomethyl Dolastatin 10 (a potent tubulin inhibitor), linked via the ADC linker Vat-Cit-PAB.
Denibulin Chemical Structure
 BCP21548 Denibulin 284019-34-7
Denibulin is a small molecular vascular disrupting agent (VDA), with potential antimitotic and antineoplastic activities. Denibulin selectively targets and reversibly binds to the colchicine-binding site on tubulin and inhibits microtubule assembly.
Vinflunine Tartrate Chemical Structure
 BCP27712 Vinflunine Tartrate 1201898-17-0
Vinflunine Tartrat is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
Soblidotin Chemical Structure
 BCP30677 Soblidotin 149606-27-9
Soblidotin is a novel synthetic Dolastatin 10 derivative and inhibitor of tubulin polymerization.
Baccatine III Chemical Structure
 BCP09552 Baccatine III 27548-93-2
Baccatin III is the precursor to paclitaxel/ taxol.
Auristatin E trifluoroacetate Chemical Structure
 BCP30132 Auristatin E trifluoroacetate AuristatinEt
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates.
Larotaxel dihydrate Chemical Structure
 BCP30123 Larotaxel dihydrate 192573-38-9
Larotaxel dihydrate has antineoplastic activity.
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