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Protease/Metabolic Enzyme
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Chemical Structure Cat. No. Product Name CAS No.
Petesicatib Chemical Structure
BCP30532 Petesicatib 1252637-35-6
Petesicatib is a cathepsin inhibitor drug candidate.
Z-Phe-Tyr(tBu)-diazomethylketone Chemical Structure
BCP29942 Z-Phe-Tyr(tBu)-diazomethylketone 114014-15-2
Z-Phe-Tyr(tBu)-diazomethylketone is an irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.
Z-Gly-Leu-Phe-CMK Chemical Structure
BCP23532 Z-Gly-Leu-Phe-CMK Z-Gly-Leu-Phe-CMK
Z-Gly-Leu-Phe-CMK is a cathepsin G inhibitor.
Balicatib Chemical Structure
BCP09098 Balicatib 354813-19-7
Balicatib, an inhibitor of the osteoclastic enzyme cathepsin K.
Leupeptin Chemical Structure
BCP10660 Leupeptin 103476-89-7
Leupeptin is a reversible inhibitor of protease with Ki values of 35 nM, 3.4 μM, 6 nM and 72 nM for bovine trypsin, human plasmin, bovine spleen cathepsin B and recombinant human calpain, respectively.
MDL28170 Chemical Structure
BCP15636 MDL28170 88191-84-8
MDL 28170 is a selective inhibitor, which inhibites calpain with Ki values of 10nM and cathepsin B with Ki values of 25 nM while does not inhibit trypsin-like serine proteases.
Odanacatib Chemical Structure
BCP01830 Odanacatib 603139-19-1
Odanacatib (MK 0822) is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
Cathepsin Inhibitor 1 Chemical Structure
BCP06025 Cathepsin Inhibitor 1 225120-65-0
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
LY3000328 Chemical Structure
BCP14297 LY3000328 1373215-15-6
LY 3000328 is a potent and selective Cathepsin S (Cat S) inhibitor with IC50 of 7.7±5.85 nM and 1.67±1.17 nM for hCat S and mCat S.
CA-074 Chemical Structure
BCP13214 CA-074 134448-10-5
CA-074 is a potent inhibitor of cathepsin B with a Ki of 2 to 5 nM.
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