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HDAC

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HDAC

Chemical Structure Cat. No. Product Name CAS No.
Sinapic acid Chemical Structure
 BCP25316 Sinapic acid 530-59-6
Sinapic acid is found in american cranberry. Sinapic acid is a common constituent of plants and fruit.
Valproic acid Chemical Structure
 BCP33204 Valproic acid 99-66-1
Valproic acid is an inhibitor of histone deacetylase (HDAC) inhibitor, which has an anticancer effect. Valproic acid was shown to induce proliferation and enhance self-renewal of hematopoietic stem cells (HSC).
ACY-957 Chemical Structure
 BCP25969 ACY-957 1609389-52-7
ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9.
CXD101 Chemical Structure
 BCP24800 CXD101 934828-12-3
CXD101 is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. CXD101 has no activity against HDAC class II. CXD101 has antitumor activity.
SIS-17 Chemical Structure
 BCP31156 SIS-17 2374313-54-7
SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM, inhibits the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.
Remetinostat Chemical Structure
 BCP30561 Remetinostat 946150-57-8
Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma.
Corin Chemical Structure
 BCP30529 Corin 1808113-09-8
Corin is a dual inhibitor of histone lysine specific demethylase (LSD1) and histone deacetylase (HDAC), with a Ki(inact) of 110 nM for LSD1 and an IC50 of 147 nM for HDAC1.
Tinostamustine hydrochloride Chemical Structure
 BCP30456 Tinostamustine hydrochloride 1793059-58-1
Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule.
ACY-775 Chemical Structure
 BCP30179 ACY-775 1375466-18-4
ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5 nM.
Divalproex sodium Chemical Structure
 BCP12800 Divalproex sodium 76584-70-8
Divalproex Sodium, consisting of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form, is a HDAC inhibitor, used in the treatment for epilepsy.
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