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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
PNU-103017 Chemical Structure
BCP36734 PNU-103017 166335-18-8
PNU-103017 is an HIV protease inhibitor.
BB-Cl-Amidine hydrochloride Chemical Structure
BCP36632 BB-Cl-Amidine hydrochloride BB-Cl-AmidineHCl
BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor.
BI-1935 Chemical Structure
BCP36628 BI-1935 940954-41-6
BI-1935 is a potent and selective inhibitor of soluble epoxide hydrolase (sEH).
PC945 Chemical Structure
BCP36481 PC945 1931946-73-4
PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively.
Retaspimycin hydrochloride Chemical Structure
BCP36508 Retaspimycin hydrochloride 857402-63-2
Retaspimycin Hydrochloride is a potent and water-soluble inhibitor of Hsp90 with EC50s of 119 nM for both Hsp90 and Grp9.
3,4-Dichloroisocoumarin Chemical Structure
BCP36465 3,4-Dichloroisocoumarin 51050-59-0
3,4-Dichloroisocoumarin is a serine protease inhibitor.
Clomethiazole Chemical Structure
BCP36337 Clomethiazole 533-45-9
Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus.
K-604 Dihydrochloride Chemical Structure
BCP36167 K-604 Dihydrochloride 217094-32-1
K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45±0.06 μM.
ZLDI-8 Chemical Structure
BCP36163 ZLDI-8 667880-38-8
ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor.
AMG 579 Chemical Structure
BCP36114 AMG 579 1227067-61-9
AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A).
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