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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
JE-2147 Chemical Structure
BCP34046 JE-2147 186538-00-1
JE-2147 is a dipeptide HIV protease inhibitor (PI) that is effective against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro.
Calpeptin Chemical Structure
BCP34012 Calpeptin 117591-20-5
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID50 of 40 nM for Calpain I in human platelets. Calpeptin is also an inhibitor of cathepsin K.
SC-43 Chemical Structure
BCP33951 SC-43 1400989-25-4
SC-43 is an agonist of Src-homology protein tyrosine phosphatase-1 (SHP-1) that inactivates STAT3 and reduces liver fibrosis.
APX-115 Chemical Structure
BCP33883 APX-115 1270084-92-8
APX-115 is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively.
GSK2795039 Chemical Structure
BCP33870 GSK2795039 1415925-18-6
GSK2795039 is the first small molecule NADPH oxidase 2 (NOX2) inhibitor.
Vonafexor Chemical Structure
BCP33693 Vonafexor 1192171-69-9
Vonafexor is a farnesoid X receptor agonist.
LY-3381916 Chemical Structure
BCP33269 LY-3381916 2166616-75-5
LY-3381916(IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
Aacocf3 Chemical Structure
BCP33391 Aacocf3 149301-79-1
AACOCF3 is a fatty acid derivative that is arachidonic acid in which the OH part of the carboxy group has been replaced by a trifluoromethyl group
TNO155 Chemical Structure
BCP33299 TNO155 1801765-04-7
TNO155 is a potent selective and orally active allosteric inhibitor of wild-type SHP2 (IC50=0.011 µM). TNO155 has the potential for the study of RTK-dependent malignancies, especially advanced solid tumors.
SR 12813 Chemical Structure
BCP25726 SR 12813 126411-39-0
SR12813 is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM.
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