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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
EN40 Chemical Structure
BCP31630 EN40 2094547-67-6
EN40 is a potent, selective, and covalent ligand which inhibits aldehyde dehydrogenase 3A1 (ALDH3A1), and impairs lung cancer pathogenicity.
DO-264 Chemical Structure
BCP31625 DO-264 2301866-59-9
DO264 is a novel ABHD12 inhibitor.
MMP-9 Inhibitor II Chemical Structure
BCP31567 MMP-9 Inhibitor II MMP-9
MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively).
Sacubitril hemicalcium salt Chemical Structure
BCP11897 Sacubitril hemicalcium salt 1369773-39-6
Sacubitril hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696.
Rilapladib Chemical Structure
BCP31473 Rilapladib 412950-08-4
Rilapladib is a selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) inhibitor with an IC50 of 230 pM.
Trifarotene Chemical Structure
BCP31392 Trifarotene 895542-09-3
Trifarotene is a retinoic acid receptor (RAR) agonist with Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively.
Tipranavir Chemical Structure
BCP22007 Tipranavir 174484-41-4
Tipranavir is an HIV-1 protease inhibitor. It has a role as a HIV protease inhibitor and an antiviral drug.
AT-007 Chemical Structure
BCP31330 AT-007 2170729-29-8
AT-007 is a central nervous system (CNS) penetrant Aldose Reductase inhibitor (ARI) in Phase 1/2 development for treatment of Galactosemia.
VP3.15 dihydrobromide Chemical Structure
BCP31222 VP3.15 dihydrobromide 1281681-33-1
VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
VP3.15 Chemical Structure
BCP31223 VP3.15 1281681-54-6
VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.
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