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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
Salvianolic acid A Chemical Structure
BCP15440 Salvianolic acid A 96574-01-5
Salvianolic acid A could protect the blood brain barrier through matrix metallopeptidase 9 (MMP-9) inhibition and anti-inflammation.
IBMX Chemical Structure
BCP13248 IBMX 28822-58-4
IBMX is a competitive nonselective phosphodiesterase inhibitor.
LG100268 Chemical Structure
BCP08283 LG100268 153559-76-3
LG100268 is a potent and selective rexinoid and retinoid-X receptor (RXR) agonist. LG100268 binds to the α, β and γ RXR receptors with an IC50 = 3-4 nM and has no activity at the RAR retinoic acid receptors.
Lactacystin Chemical Structure
BCP13243 Lactacystin 133343-34-7
Lactacystin is a specific and an irreversible inhibitor of proteasome with IC50 value of 4.8 μM.
JZL195 Chemical Structure
BCP23894 JZL195 1210004-12-8
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor with IC50 of 13 nM and 19 nM for mouse brain FAAH and MAGL respectively.
AWD-12-281 Chemical Structure
BCP12446 AWD-12-281 257892-33-4
AWD 12-281 is a strong selective phosphodiesterase 4 (PDE4) inhibitor which has potent effects in models of lung inflammation using inhalative administration.
LCI699 Chemical Structure
BCP16339 LCI699 928134-65-0
Osilodrostat (LCI699) is a potent inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 values of 2.5 and 0.7 nM, respectively.
MK-4882 Chemical Structure
BCP13058 MK-4882 1246472-08-1
MK-4882 is a potent HCV NS5A inhibitor.
Bisdemethoxycurcumin Chemical Structure
BCP08115 Bisdemethoxycurcumin 33171-05-0
Bisdemethoxycurcumin is a natural derivative of curcumin with anti-inflammatory and anti-cancer activities.
PF-04620110 Chemical Structure
BCP16812 PF-04620110 1109276-89-2
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
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