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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
MMP-9-IN-1 Chemical Structure
BCP32608 MMP-9-IN-1 502887-71-0
MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor.
DBPR108 Chemical Structure
BCP32597 DBPR108 1186426-66-3
DBPR108 is a potent and selective hepatitis C virus nonstructural protein 5A inhibitor developed for the treatment of HCV infection.
CPDA Chemical Structure
BCP32596 CPDA 1415834-63-7
CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor.
CAY10650 Chemical Structure
BCP32595 CAY10650 1233706-88-1
CAY10650 is a potent cPLA2a inhibitor, demonstrating strong anti-inflammatory effects.
BioE-1115 Chemical Structure
BCP32544 BioE-1115 1268863-35-9
BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE-1115 is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM.
IDH889 Chemical Structure
BCP32439 IDH889 1429179-07-6
IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 μM, 0.072 μM and 1.38 μM for IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC50 of 0.014 μM.
Talabostat Chemical Structure
BCP32163 Talabostat 149682-77-9
Talabostat is a potent inhibitor of DPP4, DPP8, and DPP9. Talabostat inhibits AML progression in vivo and induces lytic cell death in sensitive AML cell lines.
AEBSF HCl Chemical Structure
BCP32155 AEBSF HCl 30827-99-7 
AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
TVB-3664 Chemical Structure
BCP32098 TVB-3664 2097262-58-1
TVB-3664 is a FASN inhibitor which significantly reduces tubulin palmitoylation and mRNA expression.
MLN-4760 Chemical Structure
BCP32100 MLN-4760 305335-31-3
MLN-4760 is an angiotensin-converting (ACE2) inhibitor. In huMNCs, MLN-4760-B detected 63% ACE2 with 28-fold selectivity over ACE.
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