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Protease/Metabolic Enzyme

Chemical Structure Cat. No. Product Name CAS No.
Debio 0932 Chemical Structure
BCP27980 Debio 0932 1061318-81-7
Debio 0932 is an orally active HSP90 inhibitor, with IC50s of 100 and 103 nM for HSP90α and HSP90β, respectively.
WYC-209 Chemical Structure
BCP31032 WYC-209 2131803-90-0
WYC-209 is a novel inhibitor of tumor-repopulating cells (trcs), inducing trc apoptosis primarily via the caspase 3 pathway
Apratastat Chemical Structure
BCP27735 Apratastat 287405-51-0
Apratastat is a matrix metalloproteinase/tumour necrosis factor-α convertase inhibitor.
FT113 Chemical Structure
BCP31017 FT113 1630808-89-7
FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme.
Pevonedistat Hydrochloride Chemical Structure
BCP27667 Pevonedistat Hydrochloride 1160295-21-5
Pevonedistat hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM.
MLN4924 Chemical Structure
BCP01927 MLN4924 905579-51-3
MLN4924 (MLN-4924)is a potent and selective small molecule NEDD8-activating enzyme (NAE) inhibitor.
PDE-9 inhibitor Chemical Structure
BCP27644 PDE-9 inhibitor 1082743-70-1
PDE-9 inhibitor is useful for neurodegenerative diseases.
Benazepril HCl Chemical Structure
BCP27638 Benazepril HCl 86541-74-4
Benazepril hydrochloride is a hydrochloride salt resulting from the reaction of benazepril with 1 mol eq. of hydrogen chloride. Benazepril is a drug of the angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure.
TRC 051384 Chemical Structure
BCP29281 TRC 051384 867164-40-7
TRC051384 is a heat shock protein 70 (HSP70) inducer.
BMS-740808 Chemical Structure
BCP23400 BMS-740808 280118-23-2
BMS-740808 is a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa.
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