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JAK

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JAK

Chemical Structure Cat. No. Product Name CAS No.
PF-06826647 Chemical Structure
 BCP33615 PF-06826647 2127109-84-4
PF-06826647(Tyk2-IN-8) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain with an IC50 of 17 nM, used in the treatment of psoriasis.
FM-479 Chemical Structure
 BCP32593 FM-479 2226521-64-6
FM-479 is a negative control for FM-381 (GLXC-09922).
TCJL37 Chemical Structure
 BCP32555 TCJL37 1258294-34-6
TCJL-37 is a potent TYK2 inhibitor.
Gusacitinib HCl Chemical Structure
 BCP31676 Gusacitinib HCl GusacitinibHCl
Gusacitinib (ASN-002) is a potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM.
Gusacitinib Chemical Structure
 BCP31675 Gusacitinib 1425381-60-7
Gusacitinib (ASN-002) is a potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM.
WHI-P 97 Chemical Structure
 BCP29062 WHI-P 97 211555-05-4
WHI-P97 is a rationally designed potent inhibitor of JAK-3.
BMS-986165 Chemical Structure
 BCP30443 BMS-986165 1609392-27-9
BMS-986165 is a selective, potent, allosteric inhibitor of tyrosine kinase 2 (Tyk2).
Abrocitinib Chemical Structure
 BCP30441 Abrocitinib 1622902-68-4
Abrocitinib, also known as PF-04965842, is an oral Janus Kinase 1 inhibitor being investigated for treatment of plaque psoriasis.
JAK3-IN-6 Chemical Structure
 BCP30249 JAK3-IN-6 1443235-95-7
JAK3-IN-6 is a potent, selective irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nM.
Baricitinib trifluoroacetate Chemical Structure
 BCP16048 Baricitinib trifluoroacetate 1187594-10-0
Baricitinib, also known as INCB 028050 or LY 3009104, is an orally administered selective JAK1 andk JAK 2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK 2( 5.7 nM).
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