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CCR

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CCR

Chemical Structure Cat. No. Product Name CAS No.
CP 481715 Chemical Structure
 BCP18399 CP 481715 212790-31-3
CP 481715 a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases.
BX 513 hydrochloride Chemical Structure
 BCP27909 BX 513 hydrochloride 1216540-18-9
BX-513 hydrochloride inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM).
UCB 35625 Chemical Structure
 BCP27911 UCB 35625 301648-08-8
UCB35625 is a potent chemokine CKR-1 (CCR1) and CKR-3 (CCR3) receptor antagonist.
ZK-756326 Chemical Structure
 BCP20725 ZK-756326 874911-96-3
ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist.
ZK756326 dihydrochloride Chemical Structure
 BCP29859 ZK756326 dihydrochloride 1780259-94-0
ZK756326 dihydrochloride is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8.
SB-297006 Chemical Structure
 BCP29726 SB-297006 58816-69-6
SB-297006 is a potent and selective CCR3 antagonist (IC50 = 39 nM).
GSK2239633A Chemical Structure
 BCP29621 GSK2239633A 1240516-71-5
GSK2239633A is a CC-chemokine receptor 4 (CCR4) antagonist, which inhibits the binding of [125I]-TARC to human CCR4 with a pIC50 of 7.96 ± 0.11.
Cenicriviroc Mesylate Chemical Structure
 BCP29615 Cenicriviroc Mesylate 497223-28-6
Cenicriviroc, also known as TAK-652 and TBR-652, is a dual CCR2/CCR5 antagonist.
TAK-779 Chemical Structure
 BCP28073 TAK-779 229005-80-5
TAK-779 is a highly potent and selective nonpeptide CCR5 antagonist with a IC50 value of 1.4 nM in the binding assay, TAK-779 also inhibited the replication of macrophage (M)-tropic HIV-1 (Ba-L strain) in both MAGI-CCR5 cells and PBMCs with EC50 values of 1.2 and 3.7 nM, respectively.
TAK 779 Chemical Structure
 BCP23716 TAK 779 263765-56-6
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for the treatment of HIV infection.
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