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PI3K

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PI3K

Chemical Structure Cat. No. Product Name CAS No.
Parsaclisib Chemical Structure
 BCP33523 Parsaclisib 1426698-88-5
Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.
MDK34597 Chemical Structure
 BCP25529 MDK34597 371934-59-7
MDK34597 is a PI3K inhibitor.
Umbralisib hydrochloride Chemical Structure
 BCP24682 Umbralisib hydrochloride 1532533-78-0
Umbralisib hydrochloride is the hydrochloride salt of TGR-1202.TGR-1202 HCl is a potent PI3Kδ inhibitor.
XL-765 Chemical Structure
 BCP32612 XL-765 1123889-87-1
XL765 is a PI3K/mTOR dual kinase inhibitor and it is more potent compared to an agent that inhibits either PI3K kinase or mTOR kinase alone.
Vps34-IN-2 Chemical Structure
 BCP26194 Vps34-IN-2 1523404-29-6
Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively.
Recilisib Chemical Structure
 BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
NVP-QAV-572 Chemical Structure
 BCP27906 NVP-QAV-572 957209-68-6
NVP-QAV-572 is a potent PI3K kianse inhibitor.
Sonolisib Chemical Structure
 BCP27666 Sonolisib 502632-66-8
Sonolisib is an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity.
D-106669 Chemical Structure
 BCP27662 D-106669 938444-93-0
D 106669 is a potent and selective PI3K inhibitor.
D-87503 Chemical Structure
 BCP27634 D-87503 800394-83-6
D-87503 is a dual extracellular signaling-related kinase (ERK)/PI3K inhibitor.
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