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PI3K

Chemical Structure Cat. No. Product Name CAS No.
XL-765 Chemical Structure
 BCP32612 XL-765 1123889-87-1
XL765 is a PI3K/mTOR dual kinase inhibitor and it is more potent compared to an agent that inhibits either PI3K kinase or mTOR kinase alone.
Vps34-IN-2 Chemical Structure
 BCP26194 Vps34-IN-2 1523404-29-6
Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively.
Recilisib Chemical Structure
 BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
NVP-QAV-572 Chemical Structure
 BCP27906 NVP-QAV-572 957209-68-6
NVP-QAV-572 is a potent PI3K kianse inhibitor.
Sonolisib Chemical Structure
 BCP27666 Sonolisib 502632-66-8
Sonolisib is an improved Wortmannin analogue, is an oral, irreversible, and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). Antitumor activity.
D-106669 Chemical Structure
 BCP27662 D-106669 938444-93-0
D 106669 is a potent and selective PI3K inhibitor.
D-87503 Chemical Structure
 BCP27634 D-87503 800394-83-6
D-87503 is a dual extracellular signaling-related kinase (ERK)/PI3K inhibitor.
BGT226 Chemical Structure
 BCP26216 BGT226 915020-55-2
BGT226 is a PI3K (with IC50s of 4 nM, 63 nM and 38 nM for PI3Kα, PI3Kβ and PI3Kγ)/mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells.
VPS34 inhibitor 1 Chemical Structure
 BCP24973 VPS34 inhibitor 1 1383716-46-8
VPS34 inhibitor 1 is a potent and selective inhibitor of VPS34 (IC50= 15 nM).
WYE-687 Chemical Structure
 BCP23427 WYE-687 1062161-90-3
WYE-687 is a potent and ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM.
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