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PI3K

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PI3K

Chemical Structure Cat. No. Product Name CAS No.
PI-103 Hydrochloride Chemical Structure
 BCP36117 PI-103 Hydrochloride 371935-79-4
PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy.
Recilisib sodium Chemical Structure
 BCP35048 Recilisib sodium 922139-31-9
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
Alpelisib hydrochloride Chemical Structure
 BCP34729 Alpelisib hydrochloride 1584128-91-5
Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively.
Parsaclisib Chemical Structure
 BCP33523 Parsaclisib 1426698-88-5
Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.
MDK34597 Chemical Structure
 BCP25529 MDK34597 371934-59-7
MDK34597 is a PI3K inhibitor.
Umbralisib hydrochloride Chemical Structure
 BCP24682 Umbralisib hydrochloride 1532533-78-0
Umbralisib hydrochloride is the hydrochloride salt of TGR-1202.TGR-1202 HCl is a potent PI3Kδ inhibitor.
XL-765 Chemical Structure
 BCP32612 XL-765 1123889-87-1
XL765 is a PI3K/mTOR dual kinase inhibitor and it is more potent compared to an agent that inhibits either PI3K kinase or mTOR kinase alone.
Vps34-IN-2 Chemical Structure
 BCP26194 Vps34-IN-2 1523404-29-6
Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively.
Recilisib Chemical Structure
 BCP31296 Recilisib 334969-03-8
Recilisib is a radioprotectant, which can activate AKT, PI3K activities in cells.
NVP-QAV-572 Chemical Structure
 BCP27906 NVP-QAV-572 957209-68-6
NVP-QAV-572 is a potent PI3K kianse inhibitor.
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