Mapracorat
| CAS No. | 887375-26-0 | Cat. No. | BCP32546 |
| Name | Mapracorat | ||
| Synonyms | ZK-245186; ZK 245186; ZK245186; BOL-303242; BOL303242; BOL 303242; BOL-303242-X; | ||
| Formula | C25H26F4N2O2 | M. Wt | 462.49 |
| Description | Mapracorat is an selective glucocorticoid receptor agonists (SEGRAs) under clinical trials for the topical treatment of atopic dermatitis, inflammation following cataract surgery, and allergic conjunctivitis. Mapracorat inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Glucocorticoid Receptor | ||
Structure
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