Nelonicline

  • Chemical Properties
CAS No. 1026134-63-3 Cat. No. BCP32806
Name Nelonicline
Synonyms ABT-126; ABT126; ABT 126;
Formula C17H19N3OS M. Wt 313.42
  • Biological Activity
Description Nelonicline, aslo known as ABT-126, is an Alpha7 nicotinic acetylcholine receptor agonist and Nicotinic acetylcholine receptor agonist. Nelonicline is potentially useful for the treatment of Alzheimer's diseases. ABT-126 may be useful to reduce dyskinesias in both early- and later-stage Parkinson's disease. Accumulating evidence suggests that the α7 subtype of nicotinic acetylcholine receptors (nAChRs) plays a key role in inflammatory processes, thought to be involved in the pathophysiology of neuropsychiatric diseases, such as schizophrenia and Alzheimer's disease.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway 
Targets nAChR 

Structure

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