Amodiaquin dihydrochloride

CAS No.	69-44-3	Cat. No.	BCP34401
Name	Amodiaquin dihydrochloride
Synonyms	Amodiaquine 2HCl;Acrichin dihydrochloride;
Formula	C20H24Cl3N3O	M. Wt	428.78

Description	Amodiaquine Hydrochloride is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. Similar in structure and activity to chloroquine, amodiaquine is effective against some chloroquine-resistant strains, particularly Plasmodium falciparum, the most deadly malaria parasite. Although the mechanism of plasmodicidal action has not been fully elucidated, like other quinoline derivatives, amodiaquine likely is able to inhibit heme polymerase activity in the body. This results in accumulation of free heme, which is toxic to the parasites.
Pathways	Microbiology/Virology
Targets	Antiparasitics

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