OTS514 hydrochloride
| CAS No. | 2319647-76-0 | Cat. No. | BCP34816 |
| Name | OTS514 hydrochloride | ||
| Synonyms | OTS 514 hydrochloride;OTS514 HCl;OTS-514 HCl; | ||
| Formula | C21H20N2O2S.HCl | M. Wt | 400.92 |
| Description | OTS514 hydrochloride is a highly potent TOPK inhibitor, which inhibits TOPK kinase activity with a median inhibitory concentration (IC50) value of 2.6 nM. OTS514 hydrochloride strongly suppresses the growth of TOPK-positive cancer cells. OTS514 hydrochloride induces cell cycle arrest and apoptosis. | ||
| Pathways | MAPK Pathway | ||
| Targets | TOPK | ||
Structure
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