SR 31747
| CAS No. | 132173-07-0 | Cat. No. | BCP35688 |
| Name | SR 31747 | ||
| Synonyms | SR-31747; SR31747; SR3147A; SR-3147A; SR 3147A; | ||
| Formula | C23H35Cl2N | M. Wt | 396.44 |
| Description | SR-31747A is a synthetic peripheral sigma receptor ligand with immunomodulatory and potential antitumor activities. Although the exact mechanism by which SR31747A exerts its antitumor effects has not been fully established, SR31747A binds to and inhibits the sigma1 receptor (SR31747A-binding protein-1 or SR-BP1), human sterol isomerase (emopamil-binding protein) and the sigma2 receptor, which may result in a reduction in tumor cell proliferation and tumor cell apoptosis. In addition, this agent inhibits the production of pro-inflammatory cytokines while increasing anti-inflammatory cytokines. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Sigma Receptor | ||
Structure
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