Elexacaftor R enantiomer

  • Chemical Properties
CAS No. 2229860-99-3 Cat. No. BCP35907
Name Elexacaftor R enantiomer
Synonyms VX-445 R enantiomer;VX445 R enantiomer;VX 445 R enantiomer;
Formula C26H34F3N7O4S M. Wt 597.66
  • Biological Activity
Description Elexacaftor, also known as VX-445, is a next-generation cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore Phe508del CFTR protein function in patients with cystic fibrosis when administered with tezacaftor and ivacaftor (VX-445–tezacaftor–ivacaftor).
Pathways Ion Channel/Membrane Transporter 
Targets CFTR 

Structure

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