L-368,899 hydrochloride
| CAS No. | 160312-62-9 | Cat. No. | BCP38590 |
| Name | L-368,899 hydrochloride | ||
| Synonyms | L 368,899 hydrochloride; L368,899 hydrochloride; L368,899 HCl; | ||
| Formula | C26H43ClN4O5S2 | M. Wt | 591.23 |
| Description | L-368,899 hydrochloride is the hydrochloride salt of L-368,899, which is a non-peptide, orally active and potent oxytocin receptor antagonist with IC50 value of 8.9 nM. It displays > 40-fold selectivity over vasopressin V1a and V2 receptors. It antagonizes oxytocin-induced uterine contractions in vitro and in vivo. It may be used in the treatment of early pregnancy failure. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Oxytocin Receptor | ||
Structure
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