Proflavine hemisulfate

CAS No.	1811-28-5	Cat. No.	BCP39681
Name	Proflavine hemisulfate
Synonyms	3,6-Acridinediamine, sulfate (2:1);Proflavin hemisulfate;
Formula	2(C13H11N3).H2SO4	M. Wt	516.57

Description	Proflavine Hemisulfate is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and antiseptic purposes. Upon topical application of proflavine hemisulfate, proflavine diffuses into cells and intercalates into DNA, thereby accumulating in and staining the nucleus. During fluorescence imaging, the cell nuclei can be visualized. This allows nuclear morphometry and the identification of cancer cells. In addition, proflavine exerts its antibacterial effect by binding to bacterial DNA, thereby disrupting DNA synthesis and halting bacterial cell growth.
Pathways	Others Pathway
Targets	Vitamin D Related

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