ML318
CAS No. | 1610516-67-0 | Cat. No. | BCP41937 |
Name | ML318 | ||
Synonyms | ML 318; ML-318; | ||
Formula | C14H8F4N2 | M. Wt | 280.22 |
Description | ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions. | ||
Pathways | Microbiology/Virology | ||
Targets | Antibiotic |
Structure
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