ML318

  • Chemical Properties
CAS No. 1610516-67-0 Cat. No. BCP41937
Name ML318
Synonyms ML 318; ML-318;
Formula C14H8F4N2 M. Wt 280.22
  • Biological Activity
Description ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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