Emivirine
| CAS号 | 149950-60-7 | 货号 | BCP43681 |
| 中文名 | Emivirine | ||
| 英文名 | Emivirine | ||
| 中文别名 | |||
| 英文别名 | MKC-442; MKC442; MKC 442; DRG-0302; DRG0302; DRG 0302; I-EBU; | ||
| 分子式 | C17H22N2O3 | 分子量 | 302.37 |
| 生物活性 | Emivirine, also known as DRG-0302; I-EBU; MKC-442, is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 for the potential treatment of HIV. It is a non-nucleoside reverse transcriptase inhibitor. While emivirine showed promising antiviral activity in vitro, it failed to show sufficient efficacy in human trials. However it is still notable as an early proof of concept, which led to the discovery of a number of related antiviral drugs. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | Reverse Transcriptase | ||
结构式
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