Dynarrestin

  • Chemical Properties
CAS No. 2222768-84-3 Cat. No. BCP44170
Name Dynarrestin
Synonyms
Formula C22H23F2N3O2S M. Wt 431.5
  • Biological Activity
Description Dynarrestin is a potent and selective dynein inhibitor. Dynarrestin inhibits hedgehog signaling in vitro (IC50 = 0.22 μM). Dynarrestin exhibits reversible inhibition of cytoplasmic dynein 1-dependent microtubule binding and cytoplasmic dynein 2-dependent intraflagellar transport.
Pathways Wnt/Stem Cell 
Targets Hedgehog 

Structure

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