LY255283

  • Chemical Properties
CAS No. 117690-79-6 Cat. No. BCP45104
Name LY255283
Synonyms LY-255283;LY 255283;
Formula C19H28N4O3 M. Wt 360.45
  • Biological Activity
Description LY 255283 is a selective, competitive antagonist of BLT2 receptors (IC50 values are ~ 1 and > 10 μM at human recombinant BLT2 and BLT1 receptors respectively). Inhibits LTB4-induced contraction of lung parenchyma (pA2 = 7.2), and reduces LTB4-mediated airway obstruction in guinea pigs following i.v. and oral administration..
Pathways GPCR/G Protein 
Targets Leukotriene Receptor 

Structure

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