TGFβRI-IN-3

  • Chemical Properties
CAS No. TGFβRI-IN-3 Cat. No. BCP46471
Name TGFβRI-IN-3
Synonyms
Formula C28H23N3O2S M. Wt 465.57
  • Biological Activity
Description TGFβRI-IN-3 inhibits TGFβR1 at an IC50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 represents a highly selective TGFβR1 inhibitor that has potential applications in immuno-oncology.
Pathways TGF beta/Smad  
Targets TGF β/Smad 

Structure

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