c-di-AMP disodium

  • Chemical Properties
CAS No. 2734909-87-4 Cat. No. BCP48318
Name c-di-AMP disodium
Synonyms Cyclic diadenylate disodium; Cyclic-di-AMP disodium;
Formula C20H22N10Na2O12P2 M. Wt 702.38
  • Biological Activity
Description c-di-AMP sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses.
Related Products 54447-84-6(c-di-AMP)
Pathways Others Pathway 
Targets STING 

Structure

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