Certepetide

  • Chemical Properties
CAS No. 2580154-02-3 Cat. No. BCP49241
Name Certepetide
Synonyms CEND-1; iRGD;LSTA-1;
Formula C37H60N14O14S2 M. Wt 989.09
  • Biological Activity
Description Certepetide is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Integrin 

Structure

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