Vemtoberant

  • Chemical Properties
CAS No. 2169905-68-2 Cat. No. BCP49263
Name Vemtoberant
Synonyms APD418; APD 418; APD-418;
Formula C29H37N3O8S2 M. Wt 619.75
  • Biological Activity
Description Vemtoberant is a β3-adrenergic receptor (AdrR) antagonist for treatment of decompensated heart failure. Unlike current inotrope therapies, Vemtoberant improves cardiac contractility with minimal negative impact on heart rate, blood pressure, and myocardial oxygen consumption. Vemtoberant has undergone Phase 2 trials for those in heart failure with reduced ejection fraction.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Adrenergic Receptor 

Structure

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