Clofazimine
| CAS No. | 2030-63-9 | Cat. No. | BCP07792 |
| Name | Clofazimine | ||
| Synonyms | Lamprene; Lampren; Chlofazimine; Clofazimina; | ||
| Formula | C27H22Cl2N4 | M. Wt | 473.4 |
| Description | Clofazimine is a fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. Clofazimine works by binding to the guanine bases of bacterial DNA, thereby blocking the template function of the DNA and inhibiting bacterial proliferation. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
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Primary Clofazimine and Bedaquiline Resistance among Isolates from Patients with Multidrug-Resistant Tuberculosis
Publications Citing of Biochempartner's Clofazimine(CAS:2030-63-9) |
Structure
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