Zafirlukast

  • Chemical Properties
CAS No. 107753-78-6 Cat. No. BCP05226
Name Zafirlukast
Synonyms Accolate;ICI204219;ICI-204219;ICI 204219;
Formula C31H33N3O6S M. Wt 575.68
  • Biological Activity
Description Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily. Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages.
Pathways GPCR/G Protein 
Targets Leukotriene Receptor 

Structure

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