安倍生坦
| CAS号 | 177036-94-1 | 货号 | BCP22426 |
| 中文名 | 安倍生坦 | ||
| 英文名 | Ambrisentan | ||
| 中文别名 | 2-(4,6-二甲基嘧啶-2-基)氧基-3-甲氧基-3,3-二苯基丙酸; | ||
| 英文别名 | BSF-208075; BSF208075; BSF 208075; LU-208075; LU208075; LU 208075; | ||
| 分子式 | C22H22N2O4 | 分子量 | 378.43 |
| 生物活性 | Ambrisentan, also known as BSF-208075 and LU-208075, is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2). Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | Endothelin Receptor | ||
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服：
- 全国免费电话：400-099-8200
- 在线客服:
瀚香生物（Biochempartner) 的所有产品和服务仅用于科学研究，禁止用于人体和治疗！