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Ambrisentan 结构式

安倍生坦

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货号 :BCP22426CAS号 :177036-94-1纯度:98%
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  • 基本信息与产品描述
CAS号 177036-94-1 货号 BCP22426
中文名 安倍生坦
英文名 Ambrisentan
中文别名 2-(4,6-二甲基嘧啶-2-基)氧基-3-甲氧基-3,3-二苯基丙酸;
英文别名 BSF-208075; BSF208075; BSF 208075; LU-208075; LU208075; LU 208075;
SMILES
化学名称
分子式 C22H22N2O4 分子量 378.43
纯度 98% 配送 惯例下常温包邮
产品描述 Ambrisentan, also known as BSF-208075 and LU-208075, is a drug indicated for use in the treatment of pulmonary hypertension. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2). Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension.
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