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GABA Receptor

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GABA Receptor

结构式 货号 产品名称 CAS号
FG-7142 结构式
BCP41880 FG-7142 78538-74-6
FG-7142 is a benzodiazepine receptor ligand with anxiogenic and proconvulsant properties.
CTP-354 结构式
BCP40162 CTP-354 1213669-91-0
CTP354, also known as C-21191, is a novel deuterated subtype-selective GABA(A) modulator. CTP may be potentially useful for treatment of neuropathic pain, spasticity and anxiety disorders.
MRK-016 结构式
BCP40367 MRK-016 342652-67-9
MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator with EC50 value of 3 nM.
6-Prenylnaringenin 结构式
BCP39782 6-异戊二烯基柚皮素 68236-13-5
6-Prenylnaringenin is a trihydroxyflavanone having a structure of naringenin prenylated at C-6. It is a trihydroxyflavanone, a member of 4'-hydroxyflavanones and a (2S)-flavan-4-one. It derives from a (S)-naringenin.
Pipequaline HCl 结构式
BCP38837 盐酸哌夸林 80221-58-5
Pipequaline, also known as PK-8165, is an anxiolytic drug that was never marketed.
iGOT1-01 结构式
BCP38012 iGOT1-01 882256-55-5
iGOT1-01 is an inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1, GOT1).
Clomethiazole 结构式
BCP36337 氯美噻唑 533-45-9
Chlormethiazole is an potent and orally active GABAA agonist. Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus.
Golexanolone 结构式
BCP36048 Golexanolone 2089238-18-4
Golexanolone is a GABA-A receptor modulating steroid antagonist that selectively antagonizes the enhanced activation of GABAA receptors by neurosteroids such as allopregnanolone and THDOC.
4-Aminobutyric acid 结构式
BCP34675 4-氨基丁酸 56-12-2
Gamma-Aminobutyric Acid is a naturally occurring neurotransmitter with central nervous system (CNS) inhibitory activity. Gamma-aminobutyric acid (GABA), converted from the principal excitatory neurotransmitter glutamate in the brain, plays a role in regulating neuronal excitability by binding to its receptors, GABA-A and GABA-B, and thereby causing ion channel opening, hyperpolarization and eventually inhibition of neurotransmission.
Loreclezole 结构式
BCP33207 氯瑞唑 117857-45-1
Loreclezole, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors.
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